Sonipred
Generic Name
Prednisolone
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| sonipred 10 mg tablet | ৳ 3.24 | ৳ 32.40 |
Description
Overview of the medicine
Sonipred 10 mg Tablet contains Prednisolone, a corticosteroid used to treat a wide range of inflammatory and autoimmune conditions. It works by reducing inflammation and suppressing the immune system.
Uses & Indications
Dosage
Adults
Dosage is highly individualized based on the condition being treated and patient response. Typically, 5-60 mg daily, given as a single dose or in divided doses.
Elderly
Similar to adult dosage, but caution is advised due to increased risk of side effects.
Renal_impairment
No specific dose adjustment is usually required, but caution is advised in severe cases.
How to Take
Take orally, preferably with food or milk to minimize gastric irritation. It is often recommended to take the entire daily dose in the morning.
Mechanism of Action
Prednisolone works by binding to glucocorticoid receptors, which then modulate gene expression to inhibit the synthesis of inflammatory mediators like prostaglandins and leukotrienes, and suppress immune responses.
Pharmacokinetics
Onset
Onset of action is typically within 1-2 hours for oral administration.
Excretion
Excreted mainly by the kidneys as inactive metabolites.
Half life
Plasma half-life is 2-3 hours; biological half-life is 18-36 hours.
Absorption
Rapidly and well absorbed from the gastrointestinal tract.
Metabolism
Primarily metabolized in the liver to inactive metabolites.
Side Effects
Contraindications
- Systemic fungal infections
- Known hypersensitivity to prednisolone or any component of the formulation
Drug Interactions
Warfarin
May alter anticoagulant effects.
Antidiabetic agents
May increase blood glucose levels, requiring dose adjustment.
NSAIDs (e.g., Ibuprofen)
Increased risk of gastrointestinal ulcers/bleeding.
Diuretics (e.g., Furosemide)
Increased risk of hypokalemia.
Phenytoin, Rifampicin, Barbiturates
May decrease prednisolone levels by inducing hepatic enzymes.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Acute overdose is rare. Symptoms may include fluid retention, hypertension, and hyperglycemia. Treatment is symptomatic and supportive. Chronic overdose leads to Cushingoid features.
Pregnancy & Lactation
Pregnancy Category C/D (risk depends on dose/duration). Use only if the potential benefit justifies the potential risk to the fetus. Prednisolone passes into breast milk; use with caution in breastfeeding mothers.
Side Effects
Contraindications
- Systemic fungal infections
- Known hypersensitivity to prednisolone or any component of the formulation
Drug Interactions
Warfarin
May alter anticoagulant effects.
Antidiabetic agents
May increase blood glucose levels, requiring dose adjustment.
NSAIDs (e.g., Ibuprofen)
Increased risk of gastrointestinal ulcers/bleeding.
Diuretics (e.g., Furosemide)
Increased risk of hypokalemia.
Phenytoin, Rifampicin, Barbiturates
May decrease prednisolone levels by inducing hepatic enzymes.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Acute overdose is rare. Symptoms may include fluid retention, hypertension, and hyperglycemia. Treatment is symptomatic and supportive. Chronic overdose leads to Cushingoid features.
Pregnancy & Lactation
Pregnancy Category C/D (risk depends on dose/duration). Use only if the potential benefit justifies the potential risk to the fetus. Prednisolone passes into breast milk; use with caution in breastfeeding mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from the date of manufacture.
Availability
Pharmacies, Hospitals
Approval Status
Approved (Globally)
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Prednisolone has been extensively studied for decades, with numerous clinical trials establishing its efficacy and safety across a broad spectrum of inflammatory and autoimmune conditions.
Lab Monitoring
- Blood glucose levels (especially in diabetics)
- Electrolyte levels (potassium, sodium)
- Blood pressure monitoring
- Bone mineral density (for long-term use)
Doctor Notes
- Educate patients on the importance of not abruptly discontinuing prednisolone to avoid adrenal crisis.
- Monitor blood pressure, blood glucose, and electrolyte levels, especially during long-term therapy.
- Consider prophylactic measures for osteoporosis (e.g., calcium/vitamin D) and gastric protection if indicated.
Patient Guidelines
- Do not stop taking Sonipred abruptly, as it can lead to withdrawal symptoms or adrenal insufficiency. Always consult your doctor for tapering off the dose.
- Take Sonipred with food or milk to reduce stomach upset.
- Report any unusual symptoms such as severe mood changes, muscle weakness, or signs of infection to your doctor immediately.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Sonipred generally does not affect the ability to drive or operate machinery. However, if you experience side effects like dizziness or vision disturbances, avoid these activities.
Lifestyle Advice
- Maintain a low-sodium diet to help manage fluid retention and blood pressure.
- Consider calcium and Vitamin D supplements to protect bone health, especially during long-term therapy.
- Regular exercise, if appropriate, can help maintain muscle strength and bone density.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Sonipred Brand
Other medicines available under the same brand name
