Sonipred
Generic Name
Prednisolone Oral Solution
Manufacturer
Generic Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| sonipred 15 mg oral solution | ৳ 80.55 | N/A |
Description
Overview of the medicine
Sonipred-15-mg-oral-solution contains Prednisolone, a corticosteroid used to treat a wide range of inflammatory and autoimmune conditions.
Uses & Indications
Dosage
Adults
Initial dose 5-60 mg orally daily, adjusted based on condition severity and patient response. Often taken in divided doses or once daily.
Elderly
Lower doses may be required, close monitoring for side effects is important.
Renal_impairment
Dosage adjustment usually not necessary, but monitor for fluid retention and electrolyte imbalance.
How to Take
Orally, with food to minimize gastric irritation. Use a calibrated measuring device for accurate dosing.
Mechanism of Action
Prednisolone is a synthetic glucocorticoid with potent anti-inflammatory and immunosuppressive properties. It acts by binding to intracellular glucocorticoid receptors, modifying gene expression to inhibit inflammatory mediators and suppress immune responses.
Pharmacokinetics
Onset
Within 1-2 hours for anti-inflammatory effects.
Excretion
Excreted primarily in the urine as metabolites.
Half life
18-36 hours (biological half-life), 2-4 hours (plasma half-life).
Absorption
Rapidly and completely absorbed from the gastrointestinal tract.
Metabolism
Primarily metabolized in the liver to inactive metabolites.
Side Effects
Contraindications
- Systemic fungal infections
- Hypersensitivity to prednisolone or any component of the solution
- Live or live-attenuated vaccines during immunosuppressive doses
Drug Interactions
NSAIDs
Increased risk of gastrointestinal bleeding.
Warfarin
Altered anticoagulant effect (monitor INR).
Diuretics (thiazide, loop)
Increased potassium loss.
CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)
May increase prednisolone levels.
CYP3A4 inducers (e.g., phenobarbital, phenytoin, rifampin)
May decrease prednisolone levels.
Storage
Store at room temperature (20°C to 25°C / 68°F to 77°F), away from light and moisture. Do not freeze.
Overdose
Symptoms may include Cushingoid features, electrolyte imbalance, hypertension. Management is supportive and symptomatic.
Pregnancy & Lactation
Use during pregnancy only if potential benefit outweighs risk. Excreted in breast milk; caution advised, monitor infant for adverse effects.
Side Effects
Contraindications
- Systemic fungal infections
- Hypersensitivity to prednisolone or any component of the solution
- Live or live-attenuated vaccines during immunosuppressive doses
Drug Interactions
NSAIDs
Increased risk of gastrointestinal bleeding.
Warfarin
Altered anticoagulant effect (monitor INR).
Diuretics (thiazide, loop)
Increased potassium loss.
CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)
May increase prednisolone levels.
CYP3A4 inducers (e.g., phenobarbital, phenytoin, rifampin)
May decrease prednisolone levels.
Storage
Store at room temperature (20°C to 25°C / 68°F to 77°F), away from light and moisture. Do not freeze.
Overdose
Symptoms may include Cushingoid features, electrolyte imbalance, hypertension. Management is supportive and symptomatic.
Pregnancy & Lactation
Use during pregnancy only if potential benefit outweighs risk. Excreted in breast milk; caution advised, monitor infant for adverse effects.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from manufacturing date, refer to product label for exact expiry.
Availability
Pharmacies, hospitals
Approval Status
Approved by regulatory authorities
Patent Status
Generic, patent expired
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials support the efficacy and safety of prednisolone for its approved indications.
Lab Monitoring
- Blood glucose levels
- Electrolytes (especially potassium)
- Blood pressure
- Bone mineral density (long-term use)
- Ophthalmic exams (long-term use)
Doctor Notes
- Educate patients on proper tapering schedules to avoid adrenal crisis and withdrawal symptoms.
- Monitor blood pressure, glucose, electrolytes, and bone density during long-term therapy.
- Consider calcium and vitamin D supplementation for patients on chronic therapy.
- Advise patients to carry a steroid card during prolonged treatment.
Patient Guidelines
- Do not stop taking this medicine abruptly; taper off slowly under medical supervision.
- Report any unusual side effects to your doctor.
- Avoid close contact with people who are sick or have infections, especially chickenpox or measles.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness or visual disturbances in some patients; use caution when driving or operating machinery.
Lifestyle Advice
- Maintain a healthy diet, rich in calcium and vitamin D.
- Regular exercise, if appropriate.
- Limit sodium intake to manage fluid retention.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Sonipred Brand
Other medicines available under the same brand name
