For inhalers, shake the device well before use. Exhale fully, then inhale slowly and deeply through the mouth while pressing down on the canister. Hold breath for 5-10 seconds, then exhale slowly. Wait 1 minute before taking a second puff if prescribed. Oral forms are taken with water.

Salbutamol selectively stimulates beta-2 adrenergic receptors, primarily located in the bronchial smooth muscles. This stimulation leads to the activation of adenyl cyclase, increasing intracellular cyclic AMP (cAMP) levels. Elevated cAMP levels result in relaxation of bronchial smooth muscles, leading to bronchodilation and improved airflow.

• •Hypersensitivity to salbutamol or any component of the formulation.
• •Severe milk protein allergy (for some formulations).

Store below 30°C. Protect from frost and direct sunlight. Keep out of reach of children. Do not puncture or incinerate the canister, even when empty.

Symptoms of overdose include tachycardia, palpitations, tremor, headache, and hypokalemia. Management involves symptomatic and supportive treatment, including monitoring of serum potassium levels and cardiac function.

Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult a doctor. Caution should be exercised when administered to a nursing mother. It is unknown if salbutamol is excreted in human milk.