Tdcef
Generic Name
Cefixime
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| tdcef 200 mg capsule | ৳ 35.00 | ৳ 210.00 |
Description
Overview of the medicine
Tdcef 200 mg capsule contains Cefixime, a broad-spectrum cephalosporin antibiotic used to treat various bacterial infections.
Uses & Indications
Dosage
Adults
200 mg once daily or 200 mg twice daily depending on the severity of the infection. The duration of treatment depends on the infection type and severity.
Elderly
Similar to adult dosage, but dose adjustment may be necessary in case of renal impairment.
Renal_impairment
Dose reduction is recommended for patients with severe renal impairment (creatinine clearance <30 mL/min).
How to Take
Take the capsule orally with or without food. Swallow the capsule whole with a glass of water.
Mechanism of Action
Cefixime works by inhibiting bacterial cell wall synthesis, leading to the death of the bacteria.
Pharmacokinetics
Onset
Peak plasma concentrations reached within 2-6 hours.
Excretion
Primarily excreted by the kidneys (approximately 50% unchanged in urine).
Half life
Average plasma half-life of 3-4 hours.
Absorption
Well absorbed orally; approximately 40-50% bioavailability.
Metabolism
Minimal hepatic metabolism; largely excreted as unchanged drug.
Side Effects
Contraindications
- Hypersensitivity to Cefixime, other cephalosporins, or penicillin.
- History of severe allergic reactions to beta-lactam antibiotics.
Drug Interactions
Probenecid
May increase cefixime plasma concentrations by decreasing renal excretion.
Oral Anticoagulants (e.g., Warfarin)
May increase prothrombin time (INR), requiring careful monitoring.
Storage
Store in a cool and dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive treatment should be given. Hemodialysis or peritoneal dialysis may be beneficial in removing the drug.
Pregnancy & Lactation
Pregnancy Category B. Use with caution in pregnant or breastfeeding women. Consult a doctor before use.
Side Effects
Contraindications
- Hypersensitivity to Cefixime, other cephalosporins, or penicillin.
- History of severe allergic reactions to beta-lactam antibiotics.
Drug Interactions
Probenecid
May increase cefixime plasma concentrations by decreasing renal excretion.
Oral Anticoagulants (e.g., Warfarin)
May increase prothrombin time (INR), requiring careful monitoring.
Storage
Store in a cool and dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive treatment should be given. Hemodialysis or peritoneal dialysis may be beneficial in removing the drug.
Pregnancy & Lactation
Pregnancy Category B. Use with caution in pregnant or breastfeeding women. Consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2 to 3 years from the date of manufacture.
Availability
Available in pharmacies and hospitals
Approval Status
Approved by DGDA/FDA
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Cefixime has undergone extensive clinical trials demonstrating its efficacy and safety in various bacterial infections, including those of the respiratory and urinary tracts.
Lab Monitoring
- Renal function tests (for prolonged therapy or in patients with renal impairment)
- Complete blood count (for prolonged therapy)
Doctor Notes
- Assess patient's allergy history to cephalosporins or penicillins before prescribing.
- Adjust dosage in patients with significant renal impairment.
- Counsel patients on the importance of completing the full course of treatment.
Patient Guidelines
- Complete the entire course of medication as prescribed, even if you feel better.
- Do not share this medicine with others, even if they have similar symptoms.
- Inform your doctor about any unusual side effects or if your condition worsens.
- Avoid self-medication.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.
Driving Precautions
This medicine may cause dizziness or blurred vision. If you experience these symptoms, avoid driving or operating machinery.
Lifestyle Advice
- Maintain good hydration by drinking plenty of fluids.
- Ensure adequate rest to aid recovery.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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