Tdcef
Generic Name
Cefixime 200 mg Tablet
Manufacturer
Reputable Pharmaceutical Company
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| tdcef 200 mg tablet | ৳ 35.00 | ৳ 210.00 |
Description
Overview of the medicine
Tdcef 200 mg Tablet is a broad-spectrum antibiotic belonging to the cephalosporin class, used to treat various bacterial infections.
Uses & Indications
Dosage
Adults
200 mg orally every 12-24 hours, or 400 mg once daily, depending on the infection. Duration is typically 7-14 days.
Elderly
No specific dose adjustment required unless severe renal impairment.
Renal_impairment
Dose adjustment needed. For CrCl 21-60 mL/min, 300 mg daily. For CrCl <20 mL/min, 200 mg daily.
How to Take
May be taken with or without food. To minimize gastrointestinal upset, it can be taken with food. Swallow the tablet whole with a glass of water. Do not crush or chew.
Mechanism of Action
Cefixime works by inhibiting bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs) located inside the bacterial cell wall, thereby inhibiting the third and final stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes.
Pharmacokinetics
Onset
Within 1 hour
Excretion
Primarily renal excretion (urine) and some biliary excretion.
Half life
Approximately 3-4 hours
Absorption
Approximately 40-50% orally absorbed. Food slightly delays absorption but does not significantly affect the extent.
Metabolism
Limited metabolism; about 50% excreted unchanged in urine.
Side Effects
Contraindications
- •Hypersensitivity to Cefixime or other cephalosporins
- •History of anaphylaxis to penicillin
Drug Interactions
Warfarin
May increase prothrombin time (PT) and INR, requiring close monitoring.
Oral Contraceptives
May reduce efficacy of oral contraceptives (use alternative contraception).
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include nausea, vomiting, diarrhea, and central nervous system excitation. Management involves symptomatic and supportive care. Hemodialysis is not effective.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Excreted in breast milk in small amounts; use with caution during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24 to 36 months from manufacturing date.
Availability
Pharmacies, hospitals, clinics
Approval Status
Approved by regulatory authorities
Patent Status
Generic available, original patent expired
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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