Vecef
Generic Name
Cefixime
Manufacturer
Popular Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| vecef 1 gm injection | ৳ 80.00 | N/A |
| vecef 500 mg capsule | ৳ 12.50 | ৳ 50.00 |
| vecef 500 mg injection | ৳ 50.00 | N/A |
| vecef 125 mg suspension | ৳ 80.00 | N/A |
| vecef 125 mg pediatric drop | ৳ 50.00 | N/A |
Description
Overview of the medicine
Vecef (Cefixime) is an oral third-generation cephalosporin antibiotic used to treat various bacterial infections.
Uses & Indications
Dosage
Adults
Adults: 200-400 mg once daily or 200 mg twice daily, depending on the infection. Duration typically 7-14 days.
Elderly
No specific dosage adjustment needed for elderly patients unless severe renal impairment exists.
Renal_impairment
Dosage adjustment is necessary for patients with severe renal impairment (CrCl < 30 mL/min).
How to Take
Administer orally, with or without food. For better absorption, it can be taken with food if gastrointestinal upset occurs.
Mechanism of Action
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs).
Pharmacokinetics
Onset
Rapid
Excretion
Primarily excreted unchanged in urine (about 50%) and bile.
Half life
3-4 hours
Absorption
Approximately 40-50% absorbed orally. Food may delay absorption but does not significantly alter the extent of absorption.
Metabolism
Limited hepatic metabolism.
Side Effects
Contraindications
- Known hypersensitivity to cefixime or any other cephalosporin
- History of serious hypersensitivity reactions to penicillin
Drug Interactions
Nifedipine
May increase cefixime absorption.
Carbamazepine
May increase carbamazepine levels; monitor drug levels.
Oral anticoagulants (e.g., Warfarin)
May increase prothrombin time; monitor INR closely.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, gastric lavage may be indicated. Symptomatic and supportive treatment is recommended. Hemodialysis and peritoneal dialysis are generally not effective.
Pregnancy & Lactation
Pregnancy Category B. Use with caution during lactation; small amounts are excreted in breast milk.
Side Effects
Contraindications
- Known hypersensitivity to cefixime or any other cephalosporin
- History of serious hypersensitivity reactions to penicillin
Drug Interactions
Nifedipine
May increase cefixime absorption.
Carbamazepine
May increase carbamazepine levels; monitor drug levels.
Oral anticoagulants (e.g., Warfarin)
May increase prothrombin time; monitor INR closely.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, gastric lavage may be indicated. Symptomatic and supportive treatment is recommended. Hemodialysis and peritoneal dialysis are generally not effective.
Pregnancy & Lactation
Pregnancy Category B. Use with caution during lactation; small amounts are excreted in breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Available in pharmacies and hospitals
Approval Status
Approved by DGDA/FDA
Patent Status
Generic
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have established the efficacy and safety of cefixime for its approved indications.
Lab Monitoring
- Renal function tests (for long-term therapy or renal impairment)
- Liver function tests (if abnormalities suspected)
Doctor Notes
- Advise patients to complete the entire course of therapy.
- Assess renal function in elderly patients or those with kidney impairment.
- Monitor for signs of allergic reactions, especially in patients with penicillin allergy history.
Patient Guidelines
- Complete the full course of medication, even if symptoms improve.
- Do not skip doses or stop taking the medicine without consulting your doctor.
- Do not share this medication with others.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.
Driving Precautions
Generally safe, but if dizziness occurs, avoid driving or operating machinery.
Lifestyle Advice
- Maintain good hydration.
- Consider taking probiotics to prevent antibiotic-associated diarrhea (consult doctor).
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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