Windel
Generic Name
Montelukast
Manufacturer
Incepta Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| windel 4 mg tablet | ৳ 0.46 | ৳ 4.60 |
Description
Overview of the medicine
Montelukast is a medication used for the management of asthma and allergic rhinitis. It works by blocking leukotrienes, substances in the body that cause inflammation and tightening of airways.
Uses & Indications
Dosage
Adults
Not typically used for adults at 4 mg strength; adults usually take 10 mg.
Elderly
No specific dosage adjustment needed based on age.
Renal_impairment
No dosage adjustment needed.
Children_2_5_years
4 mg once daily in the evening.
How to Take
Take orally once daily in the evening, with or without food. For chewable tablets, chew completely before swallowing.
Mechanism of Action
Montelukast selectively antagonizes the cysteinyl leukotriene 1 (CysLT1) receptor. This blocks the action of leukotrienes, which are potent inflammatory mediators involved in asthma and allergic rhinitis.
Pharmacokinetics
Onset
Within 1 day for asthma symptoms.
Excretion
Primarily excreted in feces via bile.
Half life
Approximately 2.7 to 5.5 hours.
Absorption
Rapidly absorbed after oral administration. Peak plasma concentrations are reached in 2-4 hours.
Metabolism
Extensively metabolized in the liver by CYP2C8, CYP3A4, and CYP2C9.
Side Effects
Contraindications
- •Hypersensitivity to montelukast or any component of the formulation.
- •Acute asthma attacks (not for rescue therapy).
Drug Interactions
Rifampin
May decrease montelukast plasma concentrations.
Phenobarbital
May decrease montelukast plasma concentrations.
Storage
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
Overdose
Symptomatic and supportive treatment. No specific antidote.
Pregnancy & Lactation
Pregnancy: Use only if clearly needed. Category B. Lactation: Excreted in breast milk; use with caution.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months
Availability
Pharmacies, Hospitals
Approval Status
Approved
Patent Status
Generic available
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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