Medicine Information

Asthmolin

Name: Asthmolin
Brand: Asthmolin
Rating: 4.5 (117 reviews)

Tablet2 mgBronchodilatorsATC: R03AC02

Generic Name

Salbutamol 2 mg tablet

Manufacturer

ACME Laboratories Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
asthmolin 2 mg tablet	৳ 0.28	N/A

Description

Overview of the medicine

Asthmolin 2 mg tablet contains Salbutamol, a short-acting beta-2 adrenergic agonist, used to relieve bronchospasm in conditions like asthma and chronic obstructive pulmonary disease (COPD).

Uses & Indications

Relief of bronchospasm in asthma

Relief of bronchospasm in COPD

Prevention of exercise-induced bronchospasm

Dosage

Adults

Usually 2-4 mg three or four times daily. Maximum 8 mg four times daily.

Elderly

Initial dose of 2 mg three or four times daily, adjust based on response.

Renal_impairment

No specific dose adjustment required, but use with caution.

How to Take

Tablets should be swallowed whole with water, with or without food.

Mechanism of Action

Salbutamol selectively stimulates beta-2 adrenergic receptors in bronchial smooth muscle, leading to muscle relaxation, bronchodilation, and increased airflow. It also inhibits the release of mast cell mediators.

Pharmacokinetics

Onset

30 minutes (oral)

Excretion

Mainly via urine as metabolites and unchanged drug.

Half life

4-6 hours

Absorption

Rapidly absorbed from the gastrointestinal tract. Oral bioavailability is 50-85% due to first-pass metabolism.

Metabolism

Primarily hepatic, largely to an inactive sulfate conjugate.

Side Effects

Contraindications

Hypersensitivity to salbutamol or any component of the formulation
Threatened abortion

Drug Interactions

Diuretics

May cause hypokalemia, increasing risk of arrhythmias.

MAOIs/TCAs

Increased risk of cardiovascular effects.

Beta-blockers

May antagonize the effects of salbutamol, potentially causing severe bronchospasm.

Storage

Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.

Overdose

Symptoms include tachycardia, tremors, palpitations, hyperglycemia, and hypokalemia. Treatment is supportive and symptomatic; consider a cardioselective beta-blocker with caution for cardiac symptoms.

Pregnancy & Lactation

Use during pregnancy only if the potential benefit outweighs the potential risk to the fetus. Excreted in breast milk, use with caution in breastfeeding mothers.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

10 tablets30 tablets100 tablets

Shelf Life

Typically 36 months from manufacturing date

Availability

Pharmacies, hospitals, clinics

Approval Status

Approved by major regulatory bodies (e.g., FDA, DGDA)

Patent Status

Generic available (original patent expired)

WHO Essential Medicine

Yes

Clinical Trials

Salbutamol has undergone extensive clinical trials demonstrating its efficacy and safety in treating bronchospasm. Continuous post-marketing surveillance.

Lab Monitoring

Monitor serum potassium levels, especially in patients receiving high doses or concomitant diuretics.
Monitor blood glucose in diabetic patients.

Doctor Notes

Emphasize proper inhaler technique for inhaled formulations.
Caution against sole reliance on SABAs; ensure patients are on appropriate controller therapy for persistent asthma.
Monitor for signs of cardiovascular adverse effects, especially in patients with pre-existing conditions.

Patient Guidelines

Follow your doctor's instructions carefully.
Do not exceed the recommended dose.
Seek medical attention if symptoms worsen or do not improve.

Missed Dose Advice

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.

Driving Precautions

May cause tremor, headache, or dizziness. Exercise caution when driving or operating machinery if affected.

Lifestyle Advice

Avoid smoking to improve respiratory health.
Manage stress, as it can trigger asthma.
Maintain a healthy lifestyle with regular exercise and a balanced diet.

Alternative Medicines in Bangladesh

Similar medicines available in the market

Salmulin 2 mg tablet (Square Pharmaceuticals Ltd.)Bronchial 2 mg tablet (Beximco Pharmaceuticals Ltd.)Asthalin 2 mg tablet (Incepta Pharmaceuticals Ltd.)