Administer by slow intravenous injection over 3-4 minutes or by intravenous infusion over 30-40 minutes. Reconstitute the powder for injection as per manufacturer's instructions.

Amoxicillin inhibits bacterial cell wall synthesis. Clavulanic acid is a beta-lactamase inhibitor that prevents the destruction of amoxicillin by bacterial beta-lactamase enzymes, thus extending amoxicillin's antibacterial spectrum.

• •Hypersensitivity to penicillin or any beta-lactam antibiotic.
• •History of amoxicillin/clavulanate-associated jaundice or hepatic dysfunction.
• •Severe renal impairment (without dose adjustment).

Store in a cool, dry place below 25°C, protected from light and moisture. Reconstituted solution should be used immediately or stored in a refrigerator (2-8°C) for a limited period as per specific product instructions.

Overdose may lead to gastrointestinal symptoms and disturbances in fluid and electrolyte balance. Convulsions may occur in patients with impaired renal function or those receiving high doses. Treatment is symptomatic and supportive. Hemodialysis may be effective in removing amoxicillin and clavulanic acid from the circulation.

Pregnancy Category B. Studies in animals have not shown harm to the fetus. Use during pregnancy and lactation should be done with caution and only if clearly needed after consulting a doctor.