Avloclav

Take orally, preferably at the start of a meal to minimize potential gastrointestinal intolerance and to maximize absorption. Shake the bottle well before each use to ensure uniform dosage. Use the provided measuring spoon or cup for accurate dosing.

Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to bacterial cell lysis and death. Clavulanic acid is a beta-lactamase inhibitor that inactivates a wide range of beta-lactamase enzymes produced by resistant bacteria, thereby extending the antibacterial spectrum of amoxicillin.

• Known hypersensitivity to penicillin or any component of Avloclav
• History of severe hypersensitivity reaction (e.g., anaphylaxis) to any other beta-lactam antibacterial agent (e.g., cephalosporins, carbapenems, monobactams)
• History of cholestatic jaundice/hepatic dysfunction associated with previous co-amoxiclav therapy

Store the dry powder below 25°C in a dry place. Keep the reconstituted suspension in the refrigerator (2-8°C) and do not freeze. Keep out of reach of children.

Symptoms of overdose may include gastrointestinal symptoms such as abdominal pain, vomiting, and diarrhea. Fluid and electrolyte imbalance may also occur. In cases of severe overdose, renal impairment or convulsions may be observed. Treatment is symptomatic and supportive. Hemodialysis can remove both amoxicillin and clavulanic acid from circulation.

Pregnancy Category B. While studies in animals have not shown harm to the fetus, adequate and well-controlled studies in pregnant women are lacking. Use during pregnancy only if clearly needed. Both amoxicillin and clavulanic acid are excreted into breast milk. Use with caution in nursing mothers, as it may cause sensitization, diarrhea, candidiasis in the infant.

• Known hypersensitivity to penicillin or any component of Avloclav
• History of severe hypersensitivity reaction (e.g., anaphylaxis) to any other beta-lactam antibacterial agent (e.g., cephalosporins, carbapenems, monobactams)
• History of cholestatic jaundice/hepatic dysfunction associated with previous co-amoxiclav therapy

Store the dry powder below 25°C in a dry place. Keep the reconstituted suspension in the refrigerator (2-8°C) and do not freeze. Keep out of reach of children.

Symptoms of overdose may include gastrointestinal symptoms such as abdominal pain, vomiting, and diarrhea. Fluid and electrolyte imbalance may also occur. In cases of severe overdose, renal impairment or convulsions may be observed. Treatment is symptomatic and supportive. Hemodialysis can remove both amoxicillin and clavulanic acid from circulation.

Pregnancy Category B. While studies in animals have not shown harm to the fetus, adequate and well-controlled studies in pregnant women are lacking. Use during pregnancy only if clearly needed. Both amoxicillin and clavulanic acid are excreted into breast milk. Use with caution in nursing mothers, as it may cause sensitization, diarrhea, candidiasis in the infant.