Medicine Information

Abdolax

Name: Abdolax
Brand: Abdolax
Rating: 4.5 (117 reviews)

Oral Solution5 mgLaxativesATC: A06AB02

Generic Name

Bisacodyl 5 mg Oral Solution

Manufacturer

Reputable Pharma Co.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
abdolax 5 mg oral solution	৳ 150.00	N/A

Description

Overview of the medicine

Abdolax 5 mg Oral Solution is a stimulant laxative used for the short-term relief of occasional constipation. It works by increasing bowel movement.

Uses & Indications

Short-term relief of occasional constipation

Bowel preparation before surgery or diagnostic procedures (e.g., colonoscopy)

Management of neurogenic bowel dysfunction

Dosage

Adults

Adults and children over 10 years: 5 mg orally once daily before bedtime. May increase to 10 mg if needed, but do not exceed 10 mg daily.

Elderly

Same as adult dosage, but may require lower doses to avoid excessive laxative effects.

Renal_impairment

No specific dose adjustment required; use with caution.

How to Take

Take orally, preferably at bedtime, with a glass of water. Avoid taking with milk or antacids within one hour of administration.

Mechanism of Action

Bisacodyl acts directly on the colonic mucosa to stimulate sensory nerve endings, which increases peristaltic contractions of the colon. It also increases water and electrolyte secretion into the colon, leading to a softer stool consistency and easier defecation.

Pharmacokinetics

Onset

Oral solution: 6-12 hours.

Excretion

Mainly excreted via feces as the active metabolite and its glucuronides; a small amount is excreted renally.

Half life

Not well-defined due to minimal systemic absorption and local action, but the active metabolite desacetyl-bisacodyl has a half-life of about 16 hours.

Absorption

Minimally absorbed systemically when taken orally; primarily acts locally in the colon. Metabolized in the liver to its active form, desacetyl-bisacodyl.

Metabolism

Hydrolyzed by esterases in the small intestine and by colonic bacteria to the active metabolite, bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM), then conjugated in the liver to glucuronides.

Side Effects

Contraindications

Acute abdominal pain
Nausea or vomiting
Intestinal obstruction
Appendicitis
Severe dehydration
Undiagnosed rectal bleeding

Drug Interactions

Diuretics, corticosteroids

Increased risk of electrolyte imbalance (especially hypokalemia) with prolonged use.

Antacids, milk, proton pump inhibitors

May dissolve the enteric coating prematurely, leading to gastric irritation and dyspepsia. Administer at least 1 hour apart.

Storage

Store below 30°C, protected from light and moisture. Do not freeze. Keep out of reach of children.

Overdose

Symptoms may include abdominal pain, diarrhea, and significant fluid and electrolyte loss (especially potassium). Management involves supportive care, correction of fluid and electrolyte imbalances.

Pregnancy & Lactation

Generally considered safe for short-term use during pregnancy and lactation, as systemic absorption is minimal. Consult a doctor before use.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

30 ml bottle60 ml bottle100 ml bottle

Shelf Life

Typically 2-3 years from manufacturing date. Check package for specific expiry.

Availability

Pharmacies, Supermarkets

Approval Status

Approved

Patent Status

Generic

Clinical Trials

Extensively studied and widely used for its laxative effects. Specific trials for 'Abdolax 5 mg oral solution' might be limited, but Bisacodyl's efficacy is well-established.

Lab Monitoring

Electrolyte levels (especially potassium) if used for prolonged periods or in at-risk patients.

Doctor Notes

Educate patients on short-term use only for occasional constipation.
Advise about lifestyle modifications for chronic constipation.
Monitor electrolyte levels in patients at risk with prolonged use.

Patient Guidelines

Do not use for more than one week without consulting a doctor.
Drink plenty of fluids while using this medication.
Do not take with milk or antacids within one hour.

Missed Dose Advice

If a dose is missed, take it as soon as you remember, unless it is almost time for your next dose. Do not double the dose. It's an as-needed medication for constipation, so missing a dose is generally not critical unless used for bowel prep.