Medicine Information

Amboral

Name: Amboral
Brand: Amboral
Rating: 4.5 (117 reviews)

Pediatric Drop6 mg/mLMucolyticsATC: R05CB06

Generic Name

Ambroxol Hydrochloride

Manufacturer

Square Pharmaceuticals Ltd.

Country

Bangladesh

Loading images...

Price Details

Current market pricing information

Variant	Unit Price	Strip Price
amboral 6 mg pediatric drop	৳ 20.06	N/A

Description

Overview of the medicine

Amboral 6 mg Pediatric Drop contains Ambroxol, a mucolytic agent used to treat acute and chronic respiratory diseases associated with abnormal mucus secretion and impaired mucus transport in children. It helps thin and loosen mucus in the airways, making it easier to cough up.

Uses & Indications

Acute and chronic inflammatory diseases of the respiratory tract associated with abnormal mucus secretion and impaired mucus transport in children.

Bronchial asthma with mucostasis.

Bronchitis (acute and chronic).

Pneumonia.

Cystic fibrosis (as an adjunct).

Dosage

Adults

This specific Amboral 6 mg Pediatric Drop formulation is not typically used for adults. Adult formulations of Ambroxol are available, usually 30 mg 2-3 times daily.

Elderly

This specific Amboral 6 mg Pediatric Drop formulation is not typically used for elderly patients. Elderly patients requiring Ambroxol should use adult formulations with caution, especially with renal or hepatic impairment.

Renal_impairment

Dosage adjustment may be required in severe renal impairment. Consult a physician for appropriate dosing, especially for pediatric patients. For children 0-2 years: 0.5 mL (3 mg) 2 times daily. For children 2-5 years: 0.5 mL (3 mg) 3 times daily. For children 6-12 years: 1 mL (6 mg) 2-3 times daily or as directed by physician.

How to Take

Administer orally, preferably after meals. Use the provided calibrated dropper for accurate dosing. The drops can be given directly into the mouth or mixed with a small amount of water or fruit juice.

Mechanism of Action

Ambroxol works by stimulating serous gland secretion, increasing mucociliary clearance, and inhibiting the synthesis of acid mucopolysaccharides. It depolymerizes acid mucopolysaccharide fibers and produces a less viscous mucus, facilitating its removal.

Pharmacokinetics

Onset

Mucolytic effect usually starts within 30 minutes of oral administration.

Excretion

Mainly excreted in the urine (approximately 90% as metabolites and 10% as unchanged drug).

Half life

Plasma elimination half-life is approximately 7-12 hours.

Absorption

Rapidly and completely absorbed from the gastrointestinal tract. Peak plasma concentrations are reached within 0.5-3 hours.

Metabolism

Primarily metabolized in the liver to various inactive metabolites via first-pass metabolism.

Side Effects

Contraindications

Hypersensitivity to Ambroxol Hydrochloride or any component of the formulation.
Patients with a history of severe allergic reactions to Bromhexine (a related compound).

Drug Interactions

Cough suppressants

Should not be administered concurrently with cough suppressants, as this may lead to accumulation of secretions due to inhibited cough reflex.

Antibiotics (e.g., Amoxicillin, Cefuroxime, Erythromycin)

Ambroxol may increase the penetration of certain antibiotics into bronchial secretions, potentially enhancing their efficacy.

Storage

Store below 30°C in a dry place, protected from light and moisture. Do not freeze. Keep out of reach of children.

Overdose

Symptoms of overdose include nausea, vomiting, diarrhea, and epigastric pain. Management is primarily supportive and symptomatic. Gastric lavage may be considered if a significant amount was recently ingested.

Pregnancy & Lactation

Ambroxol is generally not recommended during the first trimester of pregnancy. Use in later trimesters and during lactation should be done with caution and only if clearly needed, under medical supervision. Consult a physician for advice.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

15 mL bottle30 mL bottle

Shelf Life

Typically 24 to 36 months from the manufacturing date, but always refer to the specific expiry date on the packaging.

Availability

Pharmacies nationwide

Approval Status

Approved

Patent Status

Generic available

WHO Essential Medicine

Yes

Clinical Trials

Ambroxol has been extensively studied in numerous clinical trials globally, demonstrating its efficacy and safety as a mucolytic and expectorant agent in both adults and pediatric populations for various respiratory conditions.

Lab Monitoring

No specific routine laboratory monitoring is required for Ambroxol.

Doctor Notes

Educate parents/caregivers on proper dropper usage for precise pediatric dosing.
Emphasize the importance of adequate hydration to enhance mucolytic effect.
Advise against co-administration with antitussives due to risk of mucus accumulation.

Patient Guidelines

Follow the prescribed dosage and duration of treatment.
Always use the provided calibrated dropper for accurate measurement.
Do not stop treatment early, even if symptoms improve, unless advised by a doctor.
Consult a doctor if symptoms worsen, persist, or if new symptoms develop.

Missed Dose Advice

If a dose is missed, administer it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose to catch up.

Driving Precautions

Ambroxol is generally not known to impair the ability to drive or operate machinery. However, individual reactions may vary. If dizziness or drowsiness occurs, avoid such activities.

Lifestyle Advice

Ensure adequate fluid intake (water, juice) to help loosen mucus and facilitate expectoration.
Avoid smoking and exposure to respiratory irritants like dust or strong fumes.
Maintain good hygiene to prevent respiratory infections.

Alternative Medicines in Bangladesh

Similar medicines available in the market

Mucolit Pediatric Drop (Opsonin Pharma)Recofol Pediatric Drop (Incepta Pharmaceuticals)Expectol Pediatric Drop (ACME Laboratories)Broxol Pediatric Drop (Beximco Pharmaceuticals)

Global Brand Names

International brand names for this medicine

Pharma Beximco

Tablet10 mg, 20 mg

View Details