Brodil
Generic Name
Salbutamol (Albuterol)
Manufacturer
Incepta Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
Variant | Unit Price | Strip Price |
---|---|---|
brodil 5 mg respirator solution | ৳ 120.36 | N/A |
Description
Overview of the medicine
Brodil 5 mg Respirator Solution contains Salbutamol, a short-acting beta2-adrenergic receptor agonist, used for the rapid relief and prevention of bronchospasm in conditions like asthma and Chronic Obstructive Pulmonary Disease (COPD). It is administered via nebulization.
Uses & Indications
Dosage
Adults
2.5-5 mg administered via nebulizer, 3-4 times daily as required. Dilute with normal saline to a total volume of 2.0-2.5 ml.
Elderly
Similar to adult dosage, but caution should be exercised and dose adjusted based on individual response and comorbidities.
Renal_impairment
Dose adjustment may be necessary in patients with severe renal impairment. Consult a physician.
How to Take
Administer using a nebulizer. The solution may be diluted with sterile normal saline before use to achieve a total volume of 2.0-2.5 ml. The nebulization typically takes 5-15 minutes. Do not inject or ingest.
Mechanism of Action
Salbutamol selectively stimulates beta2-adrenergic receptors in bronchial smooth muscle, leading to the relaxation of these muscles and subsequent bronchodilation. This action helps to open airways and improve breathing.
Pharmacokinetics
Onset
Bronchodilation within 5-15 minutes.
Excretion
Mainly excreted in urine, largely as unchanged drug and its metabolite.
Half life
Systemic half-life is 4-6 hours.
Absorption
Rapidly absorbed from the respiratory tract. Systemic absorption can occur.
Metabolism
Primarily metabolized in the liver to an inactive sulfate conjugate.
Side Effects
Contraindications
- Hypersensitivity to Salbutamol or any component of the solution
- Patients with severe heart conditions or uncontrolled hyperthyroidism
Drug Interactions
MAOIs and TCAs
May potentiate the cardiovascular effects of Salbutamol, leading to increased risk of arrhythmias.
Diuretics (e.g., Furosemide)
May exacerbate hypokalemia when used concurrently with high doses of beta2-agonists.
Beta-blockers (e.g., Propranolol)
Can antagonize the bronchodilatory effects of Salbutamol and may cause severe bronchospasm.
Storage
Store below 30°C. Protect from light. Do not freeze. Keep out of reach of children.
Overdose
Symptoms of overdose include tachycardia, palpitations, tremor, headache, hypokalemia, and hyperglycemia. Management involves symptomatic and supportive treatment, including monitoring potassium levels.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution should be exercised when administered to a nursing mother. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years from manufacturing date.
Availability
Available in pharmacies and hospitals
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Salbutamol has been extensively studied in numerous clinical trials demonstrating its efficacy and safety for the treatment of asthma and COPD.
Lab Monitoring
- Monitor serum potassium levels, especially in severe asthma exacerbations or when used with other potassium-lowering drugs.
Doctor Notes
- Educate patients on proper nebulizer technique and the difference between reliever and controller medications.
- Assess for overuse; increased use may indicate worsening asthma control.
- Monitor for cardiovascular side effects, especially in patients with pre-existing heart conditions.
Patient Guidelines
- Use exactly as prescribed by your doctor.
- Do not exceed the recommended dose or frequency of administration.
- Ensure proper nebulizer technique for effective delivery.
- Seek medical attention immediately if your breathing worsens or if the medicine becomes less effective.
Missed Dose Advice
If a dose is missed, take it as soon as you remember, unless it is almost time for your next dose. Do not double the dose to catch up.
Driving Precautions
Salbutamol may cause tremor or dizziness in some patients. Patients should be advised to exercise caution when driving or operating machinery.
Lifestyle Advice
- Avoid known asthma triggers like dust, pollen, and pet dander.
- If you smoke, quitting can significantly improve your respiratory health.
- Maintain a healthy lifestyle with regular exercise and a balanced diet.
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Global Brand Names
International brand names for this medicine
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