Byloza
Generic Name
Bilastine
Manufacturer
XYZ Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| byloza 20 mg tablet | ৳ 15.00 | ৳ 150.00 |
Description
Overview of the medicine
Bilastine is a non-sedating, long-acting H1-antihistamine used for symptomatic treatment of allergic rhinoconjunctivitis and urticaria.
Uses & Indications
Dosage
Adults
20 mg once daily
Elderly
No dose adjustment generally required.
Renal_impairment
No dose adjustment required for mild to moderate impairment. For severe impairment, caution is advised.
How to Take
Take orally, one hour before or two hours after food or fruit juice.
Mechanism of Action
Bilastine selectively antagonizes peripheral H1 receptors, blocking histamine action and thus reducing allergic symptoms.
Pharmacokinetics
Onset
30-60 minutes
Excretion
Approximately 95% excreted unchanged, about 67% in feces and 28% in urine.
Half life
14.5 hours
Absorption
Rapidly absorbed after oral administration, peak plasma concentration reached within 1 hour. Food significantly reduces bioavailability.
Metabolism
Minimally metabolized; primarily via CYP3A4, but with negligible contribution.
Side Effects
Contraindications
- Hypersensitivity to Bilastine or any component of the tablet.
- Children under 12 years of age (for 20 mg tablet).
Drug Interactions
Diltiazem
May increase bilastine exposure.
Grapefruit juice
Reduces oral bioavailability.
Ketoconazole/Erythromycin
Can increase bilastine plasma levels due to P-gp inhibition.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptomatic and supportive treatment. No specific antidote.
Pregnancy & Lactation
Use only if clearly needed and the potential benefits outweigh the potential risks to the fetus/infant. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Pharmacies
Approval Status
Approved
Patent Status
Patent protection varies by region
Clinical Trials
Extensive clinical trials have demonstrated efficacy and safety in allergic rhinitis and urticaria.
Lab Monitoring
- No specific routine lab monitoring required.
Doctor Notes
- Advise patients on proper administration (empty stomach).
- Counsel patients regarding potential mild drowsiness and driving precautions.
Patient Guidelines
- Take on an empty stomach (1 hour before or 2 hours after food/fruit juice).
- Do not exceed the recommended dose.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take two doses at once.
Driving Precautions
May cause drowsiness or dizziness. Exercise caution when driving or operating machinery.
Lifestyle Advice
- Avoid alcohol as it may enhance drowsiness.
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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