Gynositol
Generic Name
Myo-inositol 500 mg Capsule
Manufacturer
Various manufacturers (specific to brand)
Country
Global (manufactured in various countries)
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| gynositol 500 mg capsule | ৳ 75.00 | ৳ 750.00 |
Description
Overview of the medicine
Gynositol 500 mg Capsule is a dietary supplement containing Myo-inositol, a naturally occurring substance involved in various cellular processes. It is primarily used to support reproductive health in women, particularly those with Polycystic Ovary Syndrome (PCOS), by improving insulin sensitivity and hormonal balance.
Uses & Indications
Dosage
Adults
Typically 2-4 capsules (1000-2000 mg) twice daily, or as directed by a healthcare professional. Doses up to 4g (8 capsules) daily are common.
Elderly
No specific dosage adjustment required; consult a physician.
Renal_impairment
No specific dosage adjustment required for mild to moderate impairment. For severe impairment, consult a physician.
How to Take
Take orally with water, with or without food. For best results, it is often recommended to take it consistently at the same times each day.
Mechanism of Action
Myo-inositol acts as a secondary messenger in various cellular signaling pathways, particularly in insulin signal transduction. It helps to improve cellular response to insulin, thereby reducing insulin resistance. This action can lead to improved ovarian function, regulation of menstrual cycles, reduction of hyperandrogenism, and enhancement of oocyte quality in women with PCOS.
Pharmacokinetics
Onset
Effects are gradual and may take several weeks to months to become noticeable, especially for hormonal balance and menstrual regularity.
Excretion
Primarily excreted unchanged or as metabolites in the urine.
Half life
Approximately 4-6 hours (variable depending on studies and specific isomers).
Absorption
Well absorbed orally, with peak plasma concentrations reached within hours.
Metabolism
Metabolized through the inositol-phosphate pathway; excess is broken down to glucuronic acid.
Side Effects
Contraindications
- Known hypersensitivity to Myo-inositol or any components of the capsule.
Drug Interactions
Lithium
High doses of inositol might potentially interact with lithium, possibly reducing its effectiveness (primarily associated with D-chiro-inositol, but caution is advised).
Metformin
May have synergistic effects with metformin in improving insulin sensitivity in PCOS, but consult a doctor before combining.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Overdose is unlikely to cause severe toxicity. High doses may lead to mild gastrointestinal discomfort such as nausea, flatulence, or diarrhea. Treatment is generally supportive.
Pregnancy & Lactation
Myo-inositol is generally considered safe during pregnancy and lactation, and may be beneficial for preventing gestational diabetes. However, always consult your doctor before starting any supplement during these periods.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years from the date of manufacture, specific to product labeling.
Availability
Pharmacies, health stores, online
Approval Status
Marketed as a dietary supplement
Patent Status
Generally off-patent for Myo-inositol
Clinical Trials
Numerous clinical trials and studies have demonstrated the efficacy of Myo-inositol in improving insulin sensitivity, hormonal profiles, and reproductive outcomes in women with PCOS, as well as its potential role in gestational diabetes prevention.
Lab Monitoring
- No routine lab monitoring is typically required for Myo-inositol supplementation. However, if used for PCOS, regular monitoring of hormonal profiles and glucose metabolism may be part of overall disease management.
Doctor Notes
- Myo-inositol is a valuable adjunctive therapy for PCOS patients, particularly those with insulin resistance.
- Counsel patients on the importance of consistent use and lifestyle modifications for optimal benefits.
- Monitor patient progress with appropriate clinical and laboratory assessments as part of overall PCOS management.
Patient Guidelines
- Take the capsule consistently as directed by your healthcare professional.
- Do not exceed the recommended dose.
- Combine with a healthy diet and regular exercise for optimal results, especially for PCOS management.
- Inform your doctor about all other medications and supplements you are taking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Myo-inositol is not known to impair the ability to drive or operate machinery.
Lifestyle Advice
- Adopt a balanced diet rich in whole foods and low in refined sugars.
- Engage in regular physical activity.
- Manage stress effectively to support hormonal balance.
- Ensure adequate sleep.
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Global Brand Names
International brand names for this medicine
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