Itrapex

Clinical Trials

Itraconazole has undergone extensive clinical trials demonstrating its efficacy and safety in various fungal infections. Ongoing research explores new indications and drug delivery systems.

Lab Monitoring

• Liver function tests (ALT, AST, alkaline phosphatase, bilirubin) at baseline and periodically during prolonged therapy.
• Serum electrolytes, especially potassium, if there's a risk of QT prolongation.
• ECG monitoring in patients at risk of arrhythmias.

Doctor Notes

• Assess patient for risk factors of congestive heart failure prior to initiating therapy, especially with the oral solution.
• Thoroughly review patient's concomitant medications to identify potential CYP3A4 interactions.
• Educate patients on symptoms of liver dysfunction and cardiac adverse effects to report promptly.

Patient Guidelines

• Take the capsule with a full meal.
• Complete the entire course of medication as prescribed, even if symptoms improve.
• Report any new or worsening symptoms, especially signs of liver problems (e.g., unusual fatigue, dark urine, yellowing of skin/eyes) or heart failure (e.g., shortness of breath, swelling of ankles).

Missed Dose Advice

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.

Driving Precautions

Itrapex may cause dizziness, blurred vision, or hearing loss in some patients. Patients should be advised to exercise caution when driving or operating machinery until they know how the medication affects them.

Lifestyle Advice

• Maintain good personal hygiene to prevent recurrence of fungal infections.
• Avoid alcohol consumption during treatment, as it may exacerbate liver side effects.
• Avoid self-medication; consult a doctor for proper diagnosis and treatment.