Moxin
Generic Name
Amoxicillin
Manufacturer
Beximco Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| moxin 875 mg tablet | ৳ 11.64 | ৳ 116.40 |
Description
Overview of the medicine
Moxin 875 mg Tablet contains Amoxicillin, a penicillin-type antibiotic used to treat a wide range of bacterial infections. It works by stopping the growth of bacteria.
Uses & Indications
Dosage
Adults
875 mg orally every 12 hours, or 500 mg every 8 hours, depending on the severity and type of infection. For Moxin 875 mg, typically twice daily.
Elderly
Similar to adults, but dosage adjustment may be required based on renal function.
Renal_impairment
Dose reduction necessary for severe renal impairment. Consult a doctor for specific guidelines.
How to Take
Take orally with a glass of water, with or without food. Complete the full course as prescribed.
Mechanism of Action
Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to bacterial cell lysis and death.
Pharmacokinetics
Onset
Within 30-60 minutes.
Excretion
Primarily renal, with about 60-80% excreted unchanged in urine within 6 hours.
Half life
Approximately 1-1.5 hours in adults with normal renal function.
Absorption
Rapidly and well absorbed from the gastrointestinal tract, acid-stable.
Metabolism
Partially metabolized (10-25%) to inactive penicilloic acid.
Side Effects
Contraindications
- •Hypersensitivity to penicillins or any component of the formulation.
- •History of severe hypersensitivity reaction to another beta-lactam antibiotic (e.g., cephalosporins, carbapenems).
- •Infectious mononucleosis (increased risk of rash).
Drug Interactions
Warfarin
May increase INR and risk of bleeding.
Allopurinol
Increased incidence of rash, especially in patients with hyperuricemia.
Methotrexate
May increase methotrexate toxicity by reducing its renal clearance.
Oral contraceptives
May reduce the efficacy of oral contraceptives (rare).
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include nausea, vomiting, diarrhea, and electrolyte imbalance. In severe cases, crystalluria leading to renal failure has been reported. Management is symptomatic and supportive; hemodialysis can remove Amoxicillin from circulation.
Pregnancy & Lactation
Pregnancy Category B. Generally considered safe during pregnancy. Small amounts are excreted in breast milk; generally considered compatible with breastfeeding, but monitor infant for potential side effects (e.g., diarrhea, candidiasis).
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months from the date of manufacture, consult package for exact date.
Availability
Pharmacies, Hospitals
Approval Status
Widely approved (e.g., FDA, DGDA)
Patent Status
Off-patent
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine
More Medicines
Explore other medicines you might be interested in
