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Clinical Trials

Paracetamol has undergone extensive clinical trials and post-marketing surveillance for safety and efficacy over decades, establishing its role as a widely used analgesic and antipyretic.

Lab Monitoring

• Liver function tests (ALT, AST) if overdose is suspected or with long-term high-dose therapy.
• Renal function tests if long-term high-dose use or in patients with pre-existing renal impairment.

Doctor Notes

• Emphasize precise dosing for pediatric patients using appropriate measuring devices.
• Educate parents about the risks of exceeding the recommended dose and the importance of avoiding concomitant use with other paracetamol-containing products.
• Counsel on early recognition of overdose symptoms and immediate medical intervention.

Patient Guidelines

• Always follow the prescribed dose and frequency; do not exceed the recommended daily dose.
• Do not use with other paracetamol-containing products to avoid overdose.
• If symptoms persist for more than 3 days (fever) or 5 days (pain) in children, consult a doctor.

Missed Dose Advice

If a dose is missed, take it as soon as you remember, unless it is almost time for the next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Driving Precautions

Paracetamol is not known to affect the ability to drive or operate machinery.

Lifestyle Advice

• Ensure adequate hydration, especially when treating fever.
• Avoid alcohol consumption, especially during prolonged use of paracetamol, to reduce the risk of liver damage.