Medicine Information

Amoxicon

Name: Amoxicon
Brand: Amoxicon
Rating: 4.5 (117 reviews)

Capsule500 mgAntibacterial (Penicillins)ATC: J01CA04

Generic Name

Amoxicillin

Manufacturer

General Pharmaceuticals Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
amoxicon 500 mg capsule	৳ 7.50	৳ 75.00

Description

Overview of the medicine

Amoxicillin is a penicillin antibiotic used to treat a variety of bacterial infections.

Uses & Indications

Respiratory tract infections (e.g., bronchitis, pneumonia)

Urinary tract infections

Skin and soft tissue infections

Otitis media (middle ear infection)

Sinusitis

Eradication of Helicobacter pylori

Dosage

Adults

Typically 250-500 mg every 8 hours or 500-875 mg every 12 hours, depending on the infection.

Elderly

Adult dosage, but renal function should be considered.

Renal_impairment

Dosage adjustment is necessary based on creatinine clearance.

How to Take

Administer orally, with or without food. Swallow the capsule whole with water.

Mechanism of Action

Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to bacterial cell lysis and death.

Pharmacokinetics

Onset

1 to 2 hours

Excretion

Primarily excreted unchanged via urine by renal tubular secretion and glomerular filtration.

Half life

1 to 1.5 hours (in individuals with normal renal function)

Absorption

Rapidly and well absorbed from the gastrointestinal tract. Food does not significantly affect absorption.

Metabolism

Partially metabolized (10-25%) to inactive penicilloic acid.

Side Effects

Contraindications

Known hypersensitivity to penicillin or any component of the formulation.
History of severe hypersensitivity reaction to another beta-lactam antibacterial agent (e.g., cephalosporin, carbapenem, monobactam).

Drug Interactions

Warfarin

May increase the anticoagulant effect of warfarin, increasing bleeding risk.

Allopurinol

Increases the incidence of skin rash, particularly in patients with hyperuricemia.

Methotrexate

May increase methotrexate toxicity by reducing its renal excretion.

Oral contraceptives

May reduce the efficacy of oral contraceptives.

Storage

Store below 30°C. Protect from light and moisture. Keep out of reach of children.

Overdose

Overdose typically presents with gastrointestinal symptoms such as nausea, vomiting, and diarrhea. Management is symptomatic and supportive; hemodialysis may be considered in severe cases.

Pregnancy & Lactation

Pregnancy Category B. Amoxicillin is excreted in small amounts in breast milk; use with caution in breastfeeding mothers.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

10 capsules per box100 capsules per box

Shelf Life

2-3 years from manufacturing date.

Availability

Pharmacies, Hospitals

Approval Status

Approved

Patent Status

Generic available

WHO Essential Medicine

Yes

Clinical Trials

Amoxicillin is an extensively studied and well-established antibiotic. Numerous clinical trials have confirmed its efficacy and safety profile for various bacterial infections over decades of use.

Lab Monitoring

Complete blood count (rarely needed for short courses)
Renal function (for prolonged therapy or in renal impairment)
Liver function tests (for prolonged therapy or in patients with hepatic impairment)

Doctor Notes

Always check for patient history of penicillin allergy before prescribing.
Consider renal dose adjustment for patients with impaired kidney function.
Counsel patients on completing the full course to prevent resistance.

Patient Guidelines

Complete the full course of antibiotics as prescribed, even if symptoms improve.
Do not share this medicine with others.
Store at room temperature away from moisture and heat.
Contact your doctor if symptoms do not improve or worsen.

Missed Dose Advice

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take two doses at once.

Driving Precautions

Amoxicillin generally does not affect the ability to drive or operate machinery. However, if you experience dizziness or other side effects, avoid such activities.