Medicine Information

Avlomox

Name: Avlomox
Brand: Avlomox
Rating: 4.5 (117 reviews)

Oral SuspensionAmoxicillin 125 mg/5ml and Clavulanic Acid 31.25 mg/5mlPenicillins with Beta-Lactamase InhibitorsATC: J01CR02

Generic Name

Amoxicillin and Clavulanic Acid Suspension

Manufacturer

Square Pharmaceuticals Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
avlomox 125 mg suspension	৳ 70.00	N/A

Description

Overview of the medicine

Avlomox 125 mg Suspension is an antibiotic combination of Amoxicillin and Clavulanic Acid used to treat various bacterial infections in children and adults.

Uses & Indications

Upper respiratory tract infections (e.g., otitis media, sinusitis)

Lower respiratory tract infections (e.g., bronchitis, pneumonia)

Skin and soft tissue infections

Urinary tract infections

Dental infections

Dosage

Adults

Specific adult dosage forms (e.g., higher strength tablets) are usually prescribed. This suspension is primarily for pediatric use.

Elderly

Dosage adjustment may be needed based on renal function.

Renal_impairment

Dosage adjustment required; consult product leaflet or physician.

How to Take

To be taken orally. Shake the bottle well before each use. Can be taken with or without food, but taking it with food may reduce gastrointestinal discomfort. Administer using the provided measuring spoon or cup. For pediatric use, consult a physician for appropriate weight-based dosage.

Mechanism of Action

Amoxicillin is a beta-lactam antibiotic that inhibits bacterial cell wall synthesis. Clavulanic Acid is a beta-lactamase inhibitor that protects Amoxicillin from degradation by beta-lactamase enzymes produced by resistant bacteria, thus extending Amoxicillin's spectrum of activity.

Pharmacokinetics

Onset

Rapid; Peak plasma concentrations usually occur within 1-2 hours.

Excretion

Primarily excreted unchanged in the urine (amoxicillin) and renally (clavulanic acid).

Half life

Amoxicillin: approximately 1-1.5 hours; Clavulanic acid: approximately 1 hour.

Absorption

Both amoxicillin and clavulanate are well absorbed from the gastrointestinal tract after oral administration.

Metabolism

Amoxicillin is partially metabolized; Clavulanic acid is extensively metabolized.

Side Effects

Contraindications

Hypersensitivity to penicillin or other beta-lactam antibiotics
History of cholestatic jaundice/hepatic dysfunction associated with amoxicillin/clavulanate therapy

Drug Interactions

Probenecid

Increases and prolongs amoxicillin blood levels.

Allopurinol

Increased risk of skin rash.

Anticoagulants (e.g., Warfarin)

May prolong prothrombin time; monitor INR closely.

Storage

Store the dry powder below 25°C in a dry place. Once reconstituted, store in a refrigerator (2-8°C) and discard after 7-10 days. Do not freeze.

Overdose

Symptoms include gastrointestinal upset and fluid/electrolyte imbalance. Treatment is symptomatic and supportive, hemodialysis may be considered in cases of severe renal impairment.

Pregnancy & Lactation

Category B in pregnancy. Use with caution during lactation; small amounts of both amoxicillin and clavulanate are excreted in breast milk.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

60 ml suspension100 ml suspension

Shelf Life

Typically 2 years for dry powder; 7-10 days after reconstitution when stored as directed.

Availability

Pharmacies, hospitals

Approval Status

Approved by major regulatory bodies (e.g., FDA, DGDA)

Patent Status

Generic available

WHO Essential Medicine

Yes

Clinical Trials

Extensively studied in clinical trials for efficacy and safety in treating various bacterial infections in pediatric and adult populations.

Lab Monitoring

Liver function tests (for prolonged therapy or history of hepatic dysfunction)
Renal function tests (in patients with renal impairment)
Complete blood count (for prolonged therapy)

Doctor Notes

Advise parents on proper measurement and administration.
Emphasize completing the full course to prevent resistance.
Monitor for signs of allergic reactions, especially in patients with penicillin allergy history.

Patient Guidelines

Complete the full course of treatment, even if you feel better.
Shake the suspension well before each use.
Use the provided measuring device for accurate dosing.
Report any severe or persistent side effects to your doctor.

Missed Dose Advice

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.