Betabis-Plus

Clinical Trials

Clinical trials have demonstrated the efficacy and safety of Bisoprolol and Hydrochlorothiazide combination in reducing blood pressure in patients with essential hypertension. Ongoing studies may focus on long-term cardiovascular outcomes and specific patient populations.

Lab Monitoring

• Blood pressure
• Heart rate
• Serum electrolytes (potassium, sodium)
• Renal function (creatinine, GFR)
• Liver function tests

Doctor Notes

• Monitor patients for signs of heart failure exacerbation or symptomatic hypotension, especially during initial therapy and dose titration.
• Advise patients against abrupt cessation due to risk of rebound hypertension, angina, or myocardial infarction.
• Regularly assess renal function, serum electrolytes, and glucose levels.

Patient Guidelines

• Take regularly as prescribed, preferably in the morning.
• Do not stop abruptly without consulting a doctor to avoid rebound effects.
• Report any unusual side effects, especially dizziness or fainting.
• Monitor blood pressure at home if advised by your doctor.

Missed Dose Advice

Take the missed dose as soon as you remember, unless it's almost time for the next dose. Do not double the dose.

Driving Precautions

May cause dizziness or fatigue, especially at the start of treatment or when changing doses. Exercise caution when driving or operating machinery.

Lifestyle Advice

• Adopt a healthy diet (low sodium, rich in fruits/vegetables).
• Engage in regular physical activity as tolerated.
• Avoid smoking and limit alcohol intake.
• Manage stress through relaxation techniques.