Medicine Information

Bfill

Name: Bfill
Brand: Bfill
Rating: 4.5 (117 reviews)

Tablet100 mgNon-steroidal Anti-inflammatory Drug (NSAID)ATC: M01AE01

Generic Name

Bfill

Manufacturer

PharmaCorp Innovations

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
bfill 100 mg tablet	৳ 9.00	৳ 270.00

Description

Overview of the medicine

Bfill 100 mg Tablet is a non-steroidal anti-inflammatory drug (NSAID) used for the relief of mild to moderate pain, inflammation, and fever.

Uses & Indications

Mild to moderate pain relief

Inflammation associated with arthritis

Fever reduction

Dysmenorrhea

Dosage

Adults

100 mg taken orally 2-3 times daily, or as directed by a physician. Max dose 300 mg/day.

Elderly

Lower initial dose may be considered due to potential reduced renal function. Monitor closely.

Renal_impairment

Use with caution; dose adjustment may be necessary. Not recommended for severe renal impairment.

How to Take

Take orally with food or milk to minimize gastrointestinal upset. Swallow whole; do not crush or chew.

Mechanism of Action

Inhibits cyclooxygenase (COX-1 and COX-2) enzymes, leading to a reduction in prostaglandin synthesis, thereby exerting analgesic, anti-inflammatory, and antipyretic effects.

Pharmacokinetics

Onset

30-60 minutes for analgesia.

Excretion

Excreted mainly in the urine as metabolites and their conjugates, with a small amount excreted in the feces.

Half life

Approximately 2-4 hours.

Absorption

Rapidly absorbed from the gastrointestinal tract. Peak plasma concentrations are reached within 1-2 hours.

Metabolism

Primarily metabolized in the liver by oxidation and conjugation.

Side Effects

Contraindications

Hypersensitivity to Bfill or other NSAIDs
Active gastrointestinal bleeding or peptic ulcer
Severe heart failure, renal or hepatic impairment
Third trimester of pregnancy
Coronary artery bypass graft (CABG) surgery

Drug Interactions

Lithium

May increase plasma lithium levels.

Warfarin

May increase the risk of bleeding.

Diuretics

May reduce the natriuretic effect of diuretics.

ACE Inhibitors

May diminish the antihypertensive effect.

Storage

Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.

Overdose

Symptoms may include nausea, vomiting, epigastric pain, lethargy, drowsiness. Severe overdose can lead to GI bleeding, hypotension, respiratory depression, and coma. Treatment is symptomatic and supportive, including gastric lavage and activated charcoal if presented within 1 hour of ingestion.

Pregnancy & Lactation

Not recommended in the third trimester due to risk of premature closure of ductus arteriosus. Use with caution during early pregnancy and lactation only if clearly needed and benefits outweigh risks.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

10 tablets per strip30 tablets per box

Shelf Life

36 months

Availability

Pharmacies nationwide

Approval Status

Approved by DGDA

Patent Status

Patent Pending

Clinical Trials

Ongoing phase III trials for new indications. Results from phase I and II trials supported current indications.

Lab Monitoring

Complete Blood Count (CBC) for prolonged use
Renal function tests (e.g., creatinine, BUN)
Liver function tests (e.g., ALT, AST)

Doctor Notes

Advise patients to report any unusual symptoms.
Consider lowest effective dose for shortest duration.
Monitor blood pressure regularly in hypertensive patients.

Patient Guidelines

Do not exceed the recommended dose.
Inform your doctor about all other medications you are taking.
Report any signs of unusual bleeding or black, tarry stools immediately.

Missed Dose Advice

If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.