Medicine Information

biozinc-i

Name: biozinc-i
Brand: biozinc-i
Rating: 4.5 (117 reviews)

SyrupZinc 20 mg + Iron 15 mg per 5 mlMineral Supplement (Zinc & Iron combination)ATC: B03AE10

Generic Name

Zinc Sulfate Monohydrate + Ferrous Gluconate

Manufacturer

Square Pharmaceuticals Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
biozinc i syrup	৳ 50.19	N/A

Description

Overview of the medicine

Biozinc-I Syrup is a nutritional supplement combining elemental Zinc and Iron. It is used to prevent and treat deficiencies of these essential minerals, especially in conditions like malnutrition, anemia, or during periods of increased demand such as growth, pregnancy, and lactation.

Uses & Indications

Treatment and prevention of Zinc and Iron deficiencies

Nutritional support during pregnancy and lactation

Growth promotion in children with deficiencies

Adjunct therapy for various conditions like diarrhea (Zinc) and anemia (Iron)

Dosage

Adults

Adults: 10 ml (2 teaspoonfuls) once daily or as directed by physician.

Elderly

Elderly: Same as adult dosage, or as advised by physician, considering overall health status.

Renal_impairment

Renal Impairment: Consult a physician; dosage adjustment may be necessary in severe cases.

How to Take

Oral. Preferably taken after meals to minimize gastric upset. Shake the bottle well before use.

Mechanism of Action

Zinc is an essential trace element involved in numerous enzymatic reactions, protein synthesis, cell division, and immune function. Iron is crucial for hemoglobin formation, oxygen transport, and various metabolic processes. Together, they support growth, development, and overall health.

Pharmacokinetics

Onset

Nutritional effects are gradual, observed over weeks to months with consistent use.

Excretion

Zinc is primarily excreted via feces, with minor renal excretion. Iron is minimally excreted; primarily through shedding of cells (skin, gut) and menstrual blood loss in females.

Half life

Zinc: Approximately 280 days (intracellular). Iron: Not a true half-life; recycled within the body, excess stored or excreted.

Absorption

Zinc absorption varies (10-40%) depending on dietary factors and body stores, primarily in the small intestine. Iron absorption (5-35%) is regulated by body iron stores and dietary factors, mainly in the duodenum.

Metabolism

Zinc is not metabolized but integrated into proteins and enzymes. Iron is not metabolized in the traditional sense; it is incorporated into heme, stored as ferritin/hemosiderin, or transported by transferrin.

Side Effects

Contraindications

Hypersensitivity to any component
Hemochromatosis or hemosiderosis (conditions of iron overload)
Severe renal impairment (use with caution)

Drug Interactions

Antacids

May reduce absorption of iron and zinc. Take at different times.

Levothyroxine

Iron can impair levothyroxine absorption. Separate by at least 4 hours.

Calcium supplements

May reduce absorption of iron. Take at different times.

Tetracyclines & Quinolones

Zinc and Iron can decrease absorption of these antibiotics. Separate administration by at least 2-4 hours.

Storage

Store in a cool, dry place, away from direct sunlight. Do not freeze.

Overdose

Symptoms may include severe nausea, vomiting, abdominal pain, diarrhea, lethargy, and in severe cases, shock and cardiovascular collapse (due to iron toxicity). Management involves symptomatic and supportive care. Gastric lavage, chelation therapy (e.g., deferoxamine for iron) may be necessary.

Pregnancy & Lactation

Generally considered safe and beneficial during pregnancy and lactation to meet increased nutritional demands, especially if deficiencies are present. Consult a physician.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

100 ml syrup200 ml syrup

Shelf Life

24 months from manufacturing date

Availability

Pharmacies, drug stores

Approval Status

Approved by DGDA

Patent Status

Generic

WHO Essential Medicine

Yes

Clinical Trials

Extensive clinical data support the efficacy and safety of Zinc and Iron supplementation in deficiency states. Specific trials for this brand might be proprietary.

Lab Monitoring

Serum Zinc levels (if deficiency suspected)
Serum Ferritin, Transferrin Saturation, Hemoglobin (for iron status)
Complete Blood Count (CBC)

Doctor Notes

Advise patients about potential dark stools due to iron. Ensure patients are aware of possible drug interactions with antibiotics and antacids. Monitor iron and zinc levels in prolonged therapy, especially if high doses are used.

Patient Guidelines

Take with food to reduce stomach upset.
Do not exceed the recommended dose.
Keep out of reach of children.
Store at room temperature away from light and moisture.

Missed Dose Advice

If a dose is missed, take it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose.

Driving Precautions

Biozinc-I Syrup is not known to affect the ability to drive or operate machinery.

Lifestyle Advice

Maintain a balanced diet rich in fruits, vegetables, and whole grains.
Regular exercise.
Avoid excessive tea and coffee consumption around meal times to maximize iron absorption.