Medicine Information

Chemocain-A

Name: Chemocain-A
Brand: Chemocain-A
Rating: 4.5 (117 reviews)

Injection0.5% (5 mg/mL)Local AnestheticATC: N01BB02

Generic Name

chemocain-a-2-00005-injection

Manufacturer

Fictional Pharma Inc.

Country

Global

Loading images...

Price Details

Current market pricing information

Variant	Unit Price	Strip Price
chemocain a 2 00005 injection	৳ 100.00	N/A

Description

Overview of the medicine

Chemocain-A is a synthetic amide-type local anesthetic used for various procedures to temporarily block nerve impulses, providing pain relief. It acts by stabilizing the neuronal membrane and preventing the initiation and conduction of nerve impulses.

Uses & Indications

Local infiltration anesthesia

Peripheral nerve blocks

Epidural anesthesia

Spinal anesthesia

Surgical anesthesia

Dosage

Adults

Individualized based on procedure, site, depth of anesthesia required. Max single dose usually 200 mg (40 mL of 0.5% solution) without adrenaline, or 500 mg (100 mL of 0.5% solution) with adrenaline.

Elderly

Reduced dosage recommended, starting at the lower end of the adult range, due to decreased hepatic function.

Renal_impairment

No specific dose adjustment for mild to moderate impairment. Use with caution in severe renal impairment.

How to Take

Administered via injection by trained medical professionals into the skin, tissue, or near nerves, depending on the desired anesthetic effect.

Mechanism of Action

Chemocain-A stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby localizing the anesthetic action.

Pharmacokinetics

Onset

2-5 minutes (epidural/infiltration)

Excretion

Mainly excreted in urine as metabolites, small amount as unchanged drug.

Half life

1.5-3 hours

Absorption

Rapidly absorbed from injection site, systemic absorption depends on vascularity of the tissue.

Metabolism

Primarily metabolized in the liver by microsomal enzymes.

Side Effects

Contraindications

Known hypersensitivity to amide-type local anesthetics
Severe heart block
Hypovolemic shock

Drug Interactions

MAOIs/TCAs

Increased risk of hypertension if used with vasoconstrictors like epinephrine (if included in formulation).

Beta-blockers

May increase Chemocain-A levels due to reduced hepatic blood flow.

Storage

Store below 30°C. Protect from light. Do not freeze.

Overdose

Symptoms include CNS excitation (seizures), followed by depression (respiratory arrest), and cardiovascular effects (hypotension, bradycardia, cardiac arrest). Management involves maintaining airway, ventilation, treating seizures, and supporting cardiovascular function.

Pregnancy & Lactation

Use during pregnancy only if clearly needed. Excreted in breast milk in small amounts; use with caution.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

10 mL vial (single)5 x 10 mL ampoules

Shelf Life

24 months from manufacturing date.

Availability

Hospitals, Clinics, Pharmacies

Approval Status

Approved for clinical use

Patent Status

Expired

WHO Essential Medicine

Yes

Clinical Trials

Extensive clinical trials confirm safety and efficacy for various local anesthetic procedures.

Lab Monitoring

No routine lab monitoring required for typical use.
Monitor drug levels in cases of suspected toxicity or prolonged infusion.

Doctor Notes

Always aspirate before injection to prevent intravascular administration.
Monitor patient for signs of systemic toxicity during and after administration.
Adjust dose for pediatric and elderly patients.

Patient Guidelines

Inform your doctor about all medical conditions and medications.
Report any unusual symptoms immediately.
Avoid strenuous activity until anesthetic effects wear off.

Missed Dose Advice

Not applicable as Chemocain-A is typically administered by a healthcare professional as a single dose for a procedure. There is no regular dosing schedule for patients to miss a dose.