Medicine Information

Cortider

Name: Cortider
Brand: Cortider
Rating: 4.5 (117 reviews)

Cream0.1% w/wTopical CorticosteroidsATC: D07AC01

Generic Name

Betamethasone Valerate

Manufacturer

Avenue Pharma Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
cortider 1 cream	৳ 40.00	N/A

Description

Overview of the medicine

Cortider-1-cream is a topical corticosteroid used to reduce inflammation, itching, and redness associated with various skin conditions like eczema, psoriasis, and dermatitis.

Uses & Indications

Eczema

Psoriasis

Dermatitis

Pruritus

Lichen planus

Dosage

Adults

Apply a thin film to the affected skin area once or twice daily, as directed by a physician. Rub in gently and completely. Do not use for more than 2-4 weeks without medical review.

Elderly

Same as adults, but caution for thinner skin and increased absorption.

Renal_impairment

No specific dose adjustment is generally required for topical use, but caution advised with extensive use due to potential systemic absorption.

How to Take

For external use only. Apply a thin layer to the affected skin area and rub gently. Wash hands before and after application. Avoid contact with eyes and mucous membranes.

Mechanism of Action

Cortider-1-cream works by binding to glucocorticoid receptors in cells, which then modulates gene expression, leading to reduced inflammation, immunosuppression, and vasoconstriction in the skin.

Pharmacokinetics

Onset

Clinical effects usually seen within a few days.

Excretion

Mainly via kidneys, some biliary excretion.

Half life

Variable; generally short for systemic effects from topical application due to rapid metabolism.

Absorption

Systemic absorption is minimal through intact skin; however, it can be increased by occlusion, inflammation, and use on large surface areas or mucous membranes. Absorption is higher in children.

Metabolism

Primarily in the liver to inactive metabolites.

Side Effects

Contraindications

Hypersensitivity to the active substance or any excipients
Untreated cutaneous infections (viral, bacterial, fungal)
Acne vulgaris
Rosacea
Perioral dermatitis
Pruritus without inflammation

Drug Interactions

CYP3A4 inhibitors (e.g., Ritonavir, Itraconazole)

Co-administration may inhibit the metabolism of corticosteroids, leading to increased systemic exposure. Use with caution.

Storage

Store below 30°C. Do not freeze. Protect from light and moisture. Keep out of reach of children.

Overdose

Acute overdose is unlikely. Chronic overuse or misuse can lead to systemic corticosteroid effects like Cushing's syndrome, adrenal suppression, and growth retardation in children. Treatment is symptomatic and supportive. Gradual withdrawal of the steroid may be necessary.

Pregnancy & Lactation

Pregnancy: Use only if the potential benefit justifies the potential risk to the fetus. Avoid extensive use or prolonged treatment. Lactation: Corticosteroids are excreted in breast milk. Caution should be exercised, and use should be minimized.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

10 gm tube15 gm tube30 gm tube

Shelf Life

24-36 months

Availability

Pharmacies, Hospitals

Approval Status

Approved

Patent Status

Patent Expired

Clinical Trials

Extensive clinical trials have established the efficacy and safety of topical corticosteroids like Betamethasone Valerate for various inflammatory skin conditions.

Lab Monitoring

Not routinely required for topical use. For extensive or prolonged use, monitoring for systemic corticosteroid effects (e.g., adrenal function tests, blood glucose) may be considered, especially in children.

Doctor Notes

Consider potency and duration of use, especially in sensitive areas and children.
Advise patients on proper application technique and potential side effects.
Assess for underlying infections before initiating corticosteroid therapy.
Avoid abrupt discontinuation after prolonged use to prevent rebound effects.

Patient Guidelines

Apply only a thin layer to the affected area.
Do not cover the treated area with bandages or other occlusive dressings unless advised by a doctor.
Wash hands before and after application.
Avoid contact with eyes, nose, mouth, and other mucous membranes.
Do not use for longer than prescribed by your doctor.

Missed Dose Advice

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra cream to make up for a missed dose.