Medicine Information

Dysnov

Name: Dysnov
Brand: Dysnov
Rating: 4.5 (117 reviews)

Pediatric Oral Drop0.5 mg/mLAntihistamineATC: R06AX27

Generic Name

Desloratadine

Manufacturer

Square Pharmaceuticals Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
dysnov 5 mg pediatric drop	৳ 23.00	N/A

Description

Overview of the medicine

Dysnov Pediatric Drop contains Desloratadine, a non-sedating antihistamine used to relieve symptoms associated with allergic rhinitis (including seasonal and perennial allergic rhinitis) and chronic idiopathic urticaria in children. It helps alleviate sneezing, runny nose, itchy nose, itchy eyes, tearing, and skin rash.

Uses & Indications

Relief of symptoms associated with seasonal allergic rhinitis

Relief of symptoms associated with perennial allergic rhinitis

Relief of symptoms associated with chronic idiopathic urticaria

Dosage

Adults

Not applicable for pediatric drops. Adult dosage for desloratadine is typically 5 mg once daily.

Elderly

Not applicable for pediatric drops.

Renal_impairment

Dosage adjustment may be required in severe renal impairment. Consult a physician.

How to Take

Administer orally, usually once daily, with or without food. Use the provided dropper for accurate measurement. Do not exceed the recommended dose.

Mechanism of Action

Desloratadine is a long-acting tricyclic antihistamine with selective H1-receptor antagonist activity. It prevents histamine from binding to H1-receptors, thereby inhibiting the inflammatory and allergic responses mediated by histamine.

Pharmacokinetics

Onset

Within 1 hour

Excretion

Mainly excreted in urine and feces as metabolites.

Half life

Approximately 27 hours

Absorption

Rapidly absorbed after oral administration; peak plasma concentrations reached in approximately 3 hours.

Metabolism

Extensively metabolized to 3-hydroxydesloratadine, an active metabolite, primarily by CYP2C8 and CYP3A4 enzymes.

Side Effects

Contraindications

Hypersensitivity to desloratadine, loratadine, or any component of the formulation.
Children under 6 months of age.

Drug Interactions

Cimetidine

May increase plasma concentrations of desloratadine. Use with caution.

Erythromycin

May increase plasma concentrations of desloratadine. Use with caution.

Ketoconazole

May increase plasma concentrations of desloratadine. Use with caution.

Storage

Store at room temperature (below 30°C), protected from light and moisture. Do not freeze.

Overdose

In case of overdose, symptoms may include drowsiness, somnolence, and headache. Treatment should be symptomatic and supportive.

Pregnancy & Lactation

Desloratadine should be used during pregnancy only if clearly needed. It is excreted in breast milk, so caution should be exercised when administered to a nursing mother. Consult a physician.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

10 mL bottle15 mL bottle

Shelf Life

24 months (unopened). Refer to product labeling for specific shelf life after opening.

Availability

Pharmacies, Hospitals

Approval Status

Approved by regulatory authorities (e.g., FDA, DGDA)

Patent Status

Generic available

Clinical Trials

Desloratadine has undergone extensive clinical trials demonstrating its efficacy and safety in various allergic conditions, including pediatric populations. Studies confirm its rapid onset of action and sustained symptom relief.

Lab Monitoring

No specific routine lab monitoring is generally required. Liver function tests may be considered in patients with hepatic impairment.

Doctor Notes

Emphasize accurate dosing for pediatric patients using the provided dropper.
Counsel parents on differentiating allergic symptoms from common cold symptoms.

Patient Guidelines

Do not exceed the recommended dose.
Use the provided dropper for accurate measurement.
Keep out of reach of children.

Missed Dose Advice

If a dose is missed, take it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose.