Medicine Information

Fixbac

Name: Fixbac
Brand: Fixbac
Rating: 4.5 (117 reviews)

Suspension100 mg/5 mlAntibiotics (Cephalosporins), 3rd GenerationATC: J01DD08

Generic Name

Cefixime

Manufacturer

XYZ Pharmaceuticals Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
fixbac 100 mg suspension	৳ 250.00	N/A

Description

Overview of the medicine

Fixbac-100-mg-suspension contains Cefixime, a third-generation cephalosporin antibiotic, effective against a wide range of bacterial infections. It is commonly prescribed for pediatric use.

Uses & Indications

Urinary tract infections (UTIs)

Otitis media

Pharyngitis and tonsillitis

Acute bronchitis

Uncomplicated gonorrhea

Dosage

Adults

Typically not prescribed in suspension for adults; adult dosage for Cefixime is usually 200-400 mg once daily or in two divided doses.

Elderly

No specific dosage adjustment needed for elderly unless renal function is impaired. Consult physician.

Renal_impairment

Dosage adjustment is necessary for patients with severe renal impairment (creatinine clearance < 30 ml/min).

How to Take

Administer orally with or without food. Shake the bottle well before each use.

Mechanism of Action

Cefixime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to bacterial cell lysis and death.

Pharmacokinetics

Onset

Peak plasma concentrations are achieved within 2 to 6 hours after a single oral dose.

Excretion

Primarily excreted unchanged in the urine (about 50%) and bile (about 10%).

Half life

Approximately 3-4 hours.

Absorption

Approximately 40-50% orally absorbed. Absorption may be slightly delayed by food.

Metabolism

Cefixime is not extensively metabolized; some metabolites have been identified.

Side Effects

Contraindications

Hypersensitivity to cefixime or other cephalosporins
History of serious hypersensitivity reactions to penicillin

Drug Interactions

Warfarin

May increase prothrombin time; monitor INR.

Nifedipine

May increase cefixime peak plasma concentration.

Carbamazepine

May increase carbamazepine levels.

Storage

Store below 30°C in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.

Overdose

In case of overdose, gastric lavage may be indicated. Cefixime is not removed in significant quantities by hemodialysis or peritoneal dialysis. Provide supportive care.

Pregnancy & Lactation

Pregnancy Category B. Use with caution during pregnancy if clearly needed. Cefixime is excreted in small amounts into breast milk; use with caution in breastfeeding mothers.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

30 ml suspension50 ml suspension100 ml suspension

Shelf Life

24 months (unopened); Check label for reconstituted solution stability.

Availability

Available in pharmacies and hospitals

Approval Status

Approved by DGDA/FDA

Patent Status

Generic; Patent Expired

WHO Essential Medicine

Yes

Clinical Trials

Extensive clinical trials have established the efficacy and safety of Cefixime in treating a variety of bacterial infections, especially in pediatric populations.

Lab Monitoring

Renal function tests (e.g., creatinine, BUN) for prolonged therapy or in impaired patients
Complete blood counts (CBC) periodically if therapy exceeds a long duration

Doctor Notes

Emphasize adherence to the full treatment course to prevent resistance.
Advise parents on proper measurement and administration of pediatric suspension.
Consider renal function in elderly or impaired patients for dose adjustment.

Patient Guidelines

Complete the full course of medication as prescribed, even if symptoms improve.
Shake the suspension well before each use.
Do not store leftover medicine for future use.
Consult your doctor if side effects persist or worsen.

Missed Dose Advice

If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not double dose.

Driving Precautions

Cefixime may cause dizziness in some patients. Patients should be advised to exercise caution when driving or operating machinery until they are reasonably certain that cefixime does not adversely affect their ability to perform such activities.