Medicine Information

Flexibac

Name: Flexibac
Brand: Flexibac
Rating: 4.5 (117 reviews)

Tablet10 mgMuscle Relaxant (Centrally Acting)ATC: M03BX01

Generic Name

Flexibac 10 mg Tablet

Manufacturer

MediCo Pharma Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
flexibac 10 mg tablet	৳ 11.00	৳ 165.00

Description

Overview of the medicine

Flexibac 10 mg Tablet is a centrally acting muscle relaxant used for the symptomatic relief of acute painful musculoskeletal conditions associated with muscle spasm.

Uses & Indications

Symptomatic relief of acute painful musculoskeletal conditions (e.g., sprains, strains, low back pain)

Muscle spasms associated with trauma or inflammation

Adjunctive therapy in chronic painful conditions with muscle spasm

Dosage

Adults

The usual adult dose is 10 mg three times daily. May be increased to 20 mg three times daily based on response and tolerability.

Elderly

Initiate with a lower dose, e.g., 5 mg twice daily, and gradually titrate based on response and tolerability due to increased sensitivity.

Renal_impairment

Use with caution. Dosage reduction may be necessary in patients with severe renal impairment (e.g., 5 mg once or twice daily).

How to Take

Take Flexibac 10 mg Tablet orally with or without food. Swallow the tablet whole with a glass of water. Do not crush or chew.

Mechanism of Action

Flexibac acts primarily on the central nervous system to produce skeletal muscle relaxation, likely by inhibiting polysynaptic reflexes at the spinal cord level. It reduces muscle hypertonia without affecting voluntary muscle function significantly.

Pharmacokinetics

Onset

Onset of action typically occurs within 30-60 minutes.

Excretion

Mainly excreted by the kidneys, with a small portion excreted in feces. About 70% is excreted unchanged in urine.

Half life

Elimination half-life is approximately 3-6 hours.

Absorption

Rapidly and almost completely absorbed from the gastrointestinal tract after oral administration. Peak plasma concentrations are reached within 1-2 hours.

Metabolism

Primarily metabolized in the liver via oxidative pathways, with inactive metabolites.

Side Effects

Contraindications

Hypersensitivity to Flexibac or any component of the formulation
Patients with severe liver impairment
Concomitant use with Monoamine Oxidase Inhibitors (MAOIs)

Drug Interactions

Monoamine Oxidase Inhibitors (MAOIs)

Concomitant use may lead to a severe hypertensive crisis. Flexibac should not be used within 14 days of discontinuing an MAOI.

Central Nervous System (CNS) Depressants

Increased sedative effects when co-administered with alcohol, opioids, benzodiazepines, or other CNS depressants.

Storage

Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.

Overdose

Symptoms of overdose may include severe drowsiness, dizziness, confusion, nausea, vomiting, respiratory depression, and coma. Management involves supportive care, gastric lavage, and symptomatic treatment. Naloxone may be considered if respiratory depression is severe.

Pregnancy & Lactation

Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Not recommended during breastfeeding as it may be excreted in breast milk. Consult your doctor before use.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

30 tablets (3x10's blister pack)100 tablets (10x10's blister pack)

Shelf Life

36 months from the date of manufacture.

Availability

Available in pharmacies nationwide

Approval Status

Approved by Regulatory Authority

Patent Status

Patent Pending

Clinical Trials

Extensive clinical trials (Phase I, II, and III) have demonstrated the efficacy and safety of Flexibac in treating muscle spasms and associated pain.

Lab Monitoring

Liver function tests (LFTs) may be recommended for patients on prolonged therapy.
Renal function tests

Doctor Notes

Advise patients about potential sedation and to avoid activities requiring mental alertness.
Educate patients on the importance of not abruptly discontinuing the medication, especially after prolonged use.
Monitor for signs of dependence if used long-term.

Patient Guidelines

Do not exceed the prescribed dose.
Avoid alcohol and other CNS depressants while taking Flexibac.
Inform your doctor about all medications you are taking.
Do not stop the medication abruptly without consulting your doctor.

Missed Dose Advice

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Driving Precautions

Flexibac may cause drowsiness or dizziness. Avoid driving or operating heavy machinery until you know how this medication affects you.

Lifestyle Advice

Incorporate light exercise and stretching as advised by your healthcare provider.
Maintain good posture and ergonomic practices to reduce musculoskeletal strain.