Medicine Information

Fungiseb

Name: Fungiseb
Brand: Fungiseb
Rating: 4.5 (117 reviews)

Cream1% w/wAntifungalATC: D01AC01

Generic Name

fungiseb-1-01-cream

Manufacturer

Example Pharma Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
fungiseb 1 01 cream	৳ 45.00	N/A

Description

Overview of the medicine

Fungiseb 1% w/w Cream is a topical antifungal medication used to treat various fungal skin infections such as athlete's foot, jock itch, ringworm, and candidiasis.

Uses & Indications

Tinea pedis (athlete's foot)

Tinea corporis (ringworm of the body)

Tinea cruris (jock itch)

Cutaneous candidiasis

Tinea versicolor (pityriasis versicolor)

Dosage

Adults

Apply a thin layer to the affected skin area and gently rub in, 2-3 times daily for 2-4 weeks, or as directed by a physician.

Elderly

No specific dosage adjustment is required for elderly patients.

Renal_impairment

No dosage adjustment is necessary for patients with renal impairment, as systemic absorption is minimal.

How to Take

Wash and dry the affected area thoroughly before applying the cream. Apply a thin layer and gently rub it into the skin. Wash hands immediately after application, unless the hands are the area being treated. Avoid contact with eyes and mucous membranes.

Mechanism of Action

It works by inhibiting the biosynthesis of ergosterol, a vital component of fungal cell membranes. This leads to increased permeability of the fungal cell membrane, resulting in the leakage of cellular contents and ultimately the death of the fungal cell.

Pharmacokinetics

Onset

Symptom improvement typically begins within a few days, but a full course of treatment is required for complete eradication, usually 2-4 weeks.

Excretion

Metabolites are primarily excreted via the urine and feces. Systemic excretion is negligible.

Half life

Not clinically relevant for topical application due to minimal systemic absorption.

Absorption

Minimal systemic absorption occurs after topical application, with less than 0.5% of the dose reaching systemic circulation.

Metabolism

Any absorbed portion is rapidly metabolized in the liver to inactive metabolites.

Side Effects

Contraindications

Known hypersensitivity to fungiseb (clotrimazole or similar antifungal agents) or any other component of the cream.

Drug Interactions

Storage

Store below 30°C in a dry and cool place, protected from light. Keep out of reach of children.

Overdose

Overdose through topical application is unlikely. In case of accidental ingestion, seek medical attention. Do not induce vomiting.

Pregnancy & Lactation

Consult a healthcare professional before use during pregnancy or lactation. While systemic absorption is minimal, it should only be used if the potential benefit justifies the potential risk to the fetus or infant.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

10 g tube20 g tube

Shelf Life

24 months from the date of manufacture when stored correctly.

Availability

Pharmacies, drugstores

Approval Status

Approved

Patent Status

Generic available

Clinical Trials

Extensive clinical trials have established the efficacy and safety of clotrimazole (the likely active ingredient in fungiseb) in treating various superficial fungal infections.

Lab Monitoring

No specific laboratory monitoring is required for topical fungiseb cream.

Doctor Notes

Emphasize the importance of completing the full course of treatment, even if symptoms improve quickly.
Advise patients on proper hygiene practices to prevent reinfection and spread.
If no improvement is observed after 4 weeks, re-evaluate the diagnosis and consider alternative treatments.

Patient Guidelines

Complete the full course of treatment as prescribed, even if symptoms improve.
Wash your hands thoroughly before and after applying the cream.
Avoid contact with eyes, mouth, and other mucous membranes.
Do not cover the treated area with an occlusive dressing unless advised by your doctor.
If symptoms worsen or do not improve after 4 weeks, consult your doctor.

Missed Dose Advice

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not apply extra cream to make up for a missed dose.

Driving Precautions

Fungiseb 1% Cream has no known effect on the ability to drive or operate machinery.

Lifestyle Advice

Keep the affected area clean and dry.
Wear loose-fitting, breathable clothing.
Avoid sharing towels, clothing, or personal items to prevent spreading the infection.
Practice good personal hygiene.