Medicine Information

g-cipro

Name: g-cipro
Brand: g-cipro
Rating: 4.5 (117 reviews)

Injection200 mgFluoroquinolone AntibioticATC: J01MA02

Generic Name

Ciprofloxacin

Manufacturer

General Pharmaceuticals Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
g cipro 200 mg injection	৳ 50.00	N/A

Description

Overview of the medicine

G-Cipro 200 mg Injection is an antibiotic medication used to treat various bacterial infections. It belongs to a class of drugs called fluoroquinolones, which work by stopping the growth of bacteria. It is administered intravenously.

Uses & Indications

Complicated and uncomplicated urinary tract infections (UTIs)

Lower respiratory tract infections (e.g., pneumonia, bronchitis)

Skin and skin structure infections

Bone and joint infections

Intra-abdominal infections

Infectious diarrhea

Typhoid fever

Sepsis

Gonorrhea (uncomplicated)

Dosage

Adults

Usually 200 mg to 400 mg intravenously every 8 to 12 hours, depending on the severity and type of infection. Infusion time should be over 60 minutes.

Elderly

Dosage adjustments may be necessary based on renal function.

Renal_impairment

For creatinine clearance 30-50 mL/min: 200-400 mg IV every 12 hours. For creatinine clearance <30 mL/min: 200-400 mg IV every 18-24 hours.

How to Take

G-Cipro 200 mg injection is administered as an intravenous infusion over a period of 60 minutes. It should be diluted before use according to manufacturer instructions. Do not administer as a bolus injection.

Mechanism of Action

Ciprofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes necessary for bacterial DNA replication, transcription, repair, and recombination. This leads to the disruption of bacterial DNA and ultimately bacterial cell death.

Pharmacokinetics

Onset

Rapid (within minutes for IV infusion).

Excretion

Primarily renal (40-50% as unchanged drug), some fecal excretion.

Half life

Approximately 3 to 5 hours.

Absorption

Rapid and extensive absorption after intravenous administration.

Metabolism

Limited hepatic metabolism (10-20% to less active metabolites).

Side Effects

Contraindications

Hypersensitivity to ciprofloxacin or other quinolone antibiotics.
Co-administration with Tizanidine (due to risk of hypotension and somnolence).

Drug Interactions

NSAIDs

Increased risk of CNS stimulation and seizures.

Warfarin

Increased anticoagulant effect, leading to bleeding risk. Monitor INR.

Tizanidine

Increased risk of hypotension and somnolence. Concomitant use is contraindicated.

Cyclosporine

Increased serum creatinine levels. Monitor renal function.

Theophylline

Increased plasma levels of Theophylline, leading to toxicity. Monitor Theophylline levels.

QT-prolonging drugs

Increased risk of QT prolongation and arrhythmia.

Storage

Store below 30°C. Do not freeze. Protect from light. Keep out of reach of children.

Overdose

In case of overdose, supportive care is recommended. Gastric lavage and emesis may be considered. Maintain adequate hydration. Hemodialysis or peritoneal dialysis remove only a small amount of ciprofloxacin from the body.

Pregnancy & Lactation

Pregnancy Category C. Ciprofloxacin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Ciprofloxacin is excreted into breast milk and can cause serious adverse reactions in nursing infants; therefore, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

100 mL vial (2 mg/mL)

Shelf Life

Typically 24-36 months from the date of manufacture. Refer to the specific product packaging for exact shelf life.

Availability

Available in pharmacies and hospitals

Approval Status

Approved by major regulatory bodies (e.g., FDA, DGDA)

Patent Status

Off-patent

WHO Essential Medicine

Yes

Clinical Trials

Ciprofloxacin has undergone extensive clinical trials demonstrating its efficacy and safety across various bacterial infections. Ongoing research continues to evaluate its use in emerging resistant strains and new indications.

Lab Monitoring

Renal function tests (creatinine, BUN)
Liver function tests (ALT, AST)
Complete blood count (CBC)
Electrolytes (especially potassium and magnesium if QT prolongation risk)

Doctor Notes

Monitor patients for signs of tendonitis/rupture, especially in the elderly and those on corticosteroids.
Assess renal function prior to and during treatment, especially in patients with pre-existing impairment.
Caution in patients with known or suspected CNS disorders due to increased risk of seizures.

Patient Guidelines

Complete the full course of antibiotics as prescribed by your doctor, even if symptoms improve.
Report any unusual side effects, especially joint pain, numbness, tingling, or severe diarrhea.
Inform your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements.

Missed Dose Advice

If a dose of this medicine is missed, it should be taken as soon as remembered. However, if it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose.

Driving Precautions

This medicine may cause dizziness or lightheadedness. Avoid driving or operating heavy machinery until you know how this medicine affects you.

Lifestyle Advice

Maintain good hydration by drinking plenty of fluids.
Avoid prolonged exposure to sunlight or artificial UV light as ciprofloxacin can increase photosensitivity.

Alternative Medicines in Bangladesh

Similar medicines available in the market

Ciprocin (Square Pharmaceuticals Ltd.)Ciprobid (Incepta Pharmaceuticals Ltd.)Floxin (Renata Limited)Cipronex (Beximco Pharmaceuticals Ltd.)

Global Brand Names

International brand names for this medicine

Reputable Pharma Ltd.

TabletVaries (e.g., Vitamin A 5000 IU, Vitamin C 60 mg, Zinc 15 mg)

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