Medicine Information

Hemocal-LD

Name: Hemocal-LD
Brand: Hemocal-LD
Rating: 4.5 (117 reviews)

Rectal Ointment4% Lidocaine Hydrochloride and 2% Hydrocortisone AcetateAntihemorrhoidals with CorticosteroidsATC: C05AX03

Generic Name

Lidocaine Hydrochloride and Hydrocortisone Acetate

Manufacturer

Example Pharma Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
hemocal ld 4 2 rectal ointment	৳ 160.00	N/A

Description

Overview of the medicine

Hemocal-LD 4-2 Rectal Ointment is a combination medication containing Lidocaine Hydrochloride and Hydrocortisone Acetate. It is used for the symptomatic relief of pain, itching, swelling, and discomfort associated with hemorrhoids and other anorectal disorders.

Uses & Indications

Relief of pain, itching, burning, and discomfort associated with internal and external hemorrhoids.

Treatment of anal fissures.

Management of proctitis and other anorectal inflammations and irritations.

Dosage

Adults

Apply a small amount to the affected area 2 to 3 times daily. For internal hemorrhoids, use the applicator and insert a small amount into the rectum 2 to 3 times daily, preferably after bowel movements.

Elderly

Similar to adult dosage, but use with caution and under medical advice, especially if other medical conditions are present.

Renal_impairment

No specific dosage adjustment is typically required for topical application due to minimal systemic absorption.

How to Take

For external or intrarectal use only. Wash and dry the affected area thoroughly before application. Apply a thin layer of ointment. For intrarectal application, attach the provided applicator to the tube, insert gently into the rectum, and squeeze. Wash hands thoroughly before and after use.

Mechanism of Action

Lidocaine, a local anesthetic, blocks nerve impulse conduction, thereby providing temporary pain relief and reducing itching. Hydrocortisone, a corticosteroid, acts as an anti-inflammatory agent, reducing swelling and irritation by suppressing the immune response in the affected area.

Pharmacokinetics

Onset

Local anesthetic effect typically within 5-10 minutes.

Excretion

Metabolites are primarily excreted via urine.

Half life

Systemic half-life for Lidocaine is approximately 1.5-2 hours, and for Hydrocortisone, it's about 1-2 hours. However, systemic absorption from rectal application is generally low.

Absorption

Minimal systemic absorption occurs when applied topically to intact skin or mucous membranes. Absorption can increase with inflamed, abraded, or broken skin/mucosa.

Metabolism

Lidocaine is primarily metabolized in the liver. Hydrocortisone is metabolized locally in the skin and liver.

Side Effects

Contraindications

Hypersensitivity to Lidocaine, Hydrocortisone, or any other components of the ointment.
Infections (bacterial, viral, fungal) in the treatment area without concomitant anti-infective therapy.
Children under 12 years of age without medical supervision.

Drug Interactions

Other Local Anesthetics

Systemic interactions are unlikely due to minimal absorption. However, caution should be exercised if other lidocaine-containing products or local anesthetics are used concurrently in large amounts or over prolonged periods, as systemic effects could potentially accumulate.

Corticosteroids (systemic)

Rarely, if significant systemic absorption of hydrocortisone occurs, it could contribute to systemic corticosteroid effects, especially in patients already on systemic steroids.

Storage

Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach and sight of children.

Overdose

Systemic overdose is highly unlikely with proper topical use. Excessive application may lead to local irritation, burning, or stinging. If significant systemic absorption occurs (e.g., from prolonged use over large, broken areas), symptoms might include central nervous system effects (dizziness, drowsiness, nervousness) or cardiovascular effects (bradycardia, hypotension). In case of accidental ingestion or suspected systemic overdose, seek immediate medical attention.

Pregnancy & Lactation

Use Hemocal-LD with caution during pregnancy and lactation. It should only be used if the potential benefit outweighs the potential risk to the fetus or infant, and under strict medical supervision. Consult a doctor before use.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

15 gm tube30 gm tube

Shelf Life

24-36 months from the manufacturing date, typically as indicated on the packaging.

Availability

Pharmacies nationwide

Approval Status

Approved

Patent Status

Generic

Clinical Trials

Specific clinical trial data for 'Hemocal-LD 4-2 Rectal Ointment' may not be publicly available for this brand. However, the efficacy and safety of its active ingredients (Lidocaine and Hydrocortisone) in treating hemorrhoids are well-established through numerous clinical studies.

Lab Monitoring

Not typically required for localized topical use of this ointment.

Doctor Notes

Emphasize to patients the importance of adhering to the prescribed duration of treatment (typically not more than 7 days) to minimize local and systemic side effects.
Advise patients on lifestyle modifications, including dietary changes and hydration, to manage hemorrhoid symptoms effectively.
Educate patients on proper hygiene and application techniques for optimal efficacy and safety.

Patient Guidelines

Do not use for more than 7 consecutive days unless specifically directed by a healthcare professional.
Avoid contact with eyes. If contact occurs, rinse thoroughly with water.
Wash hands thoroughly before and after applying the ointment.
If symptoms do not improve within 7 days or worsen, consult your doctor.
Do not exceed the recommended dose or frequency of application.

Missed Dose Advice

If you miss a dose, apply it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra ointment to make up for a missed dose.

Driving Precautions

Hemocal-LD 4-2 Rectal Ointment is for topical use and is not expected to affect your ability to drive or operate machinery.

Lifestyle Advice

Maintain a diet rich in fiber to prevent constipation and straining during bowel movements.
Drink plenty of fluids to keep stools soft and easy to pass.
Avoid prolonged sitting or standing.
Practice good anal hygiene and avoid excessive wiping or harsh soaps.