Levamolin
Generic Name
Levamolin
Manufacturer
MediCorp Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
Variant | Unit Price | Strip Price |
---|---|---|
levamolin 5 mg tablet | ৳ 9.00 | ৳ 126.00 |
Description
Overview of the medicine
Levamolin 5 mg tablet is an antihistamine used to relieve symptoms of allergies such as sneezing, runny nose, itchy eyes, and skin rashes.
Uses & Indications
Dosage
Adults
5 mg once daily, preferably in the evening.
Elderly
Generally, no dosage adjustment needed unless renal impairment is present.
Renal_impairment
Reduce dose to 5 mg every other day for moderate to severe impairment (CrCl 10-50 mL/min).
How to Take
Take orally with or without food. Swallow the tablet whole with water. Do not chew or crush.
Mechanism of Action
Levamolin selectively blocks peripheral H1 receptors, thereby preventing histamine from binding to these receptors and reducing allergic symptoms.
Pharmacokinetics
Onset
30-60 minutes
Excretion
Mainly via urine, some via feces.
Half life
Approximately 8-12 hours
Absorption
Rapidly absorbed from the gastrointestinal tract, peak plasma concentrations reached within 1-2 hours.
Metabolism
Primarily hepatic, extensive metabolism via CYP450 enzymes.
Side Effects
Contraindications
- Hypersensitivity to levamolin or any component of the tablet
- Severe renal impairment (CrCl < 10 mL/min)
Drug Interactions
Erythromycin, Ketoconazole
May increase plasma concentrations of levamolin, potentially leading to increased side effects.
CNS Depressants (e.g., alcohol, sedatives)
May enhance CNS depressant effects, increasing drowsiness.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach and sight of children.
Overdose
Symptoms may include drowsiness, tachycardia, headache, and anticholinergic effects. Treatment is symptomatic and supportive; gastric lavage or activated charcoal may be considered if recent ingestion.
Pregnancy & Lactation
Use during pregnancy only if clearly needed and the benefit outweighs the potential risk. Excreted in breast milk, use with caution during lactation and consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date
Availability
Pharmacies, hospitals, clinics
Approval Status
Approved by national regulatory authority
Patent Status
Patented
Clinical Trials
Extensive Phase III clinical trials demonstrated the efficacy and safety of Levamolin for the treatment of allergic rhinitis and chronic idiopathic urticaria across diverse patient populations. Post-marketing surveillance is ongoing.
Lab Monitoring
- No routine lab monitoring required for healthy individuals. Liver and kidney function tests may be considered in patients with pre-existing conditions or during long-term use.
- Monitor electrolyte levels in patients with cardiovascular risk factors.
Doctor Notes
- Advise patients regarding the potential for drowsiness and its impact on driving or operating machinery.
- Consider renal dose adjustment in elderly or renally impaired patients (CrCl < 50 mL/min).
- Counsel patients on avoiding alcohol and other CNS depressants while on levamolin therapy.
- Monitor for signs of hypersensitivity reactions and advise patients to discontinue use if they occur.
Patient Guidelines
- Do not exceed the recommended dose.
- Inform your doctor about all other medications, including over-the-counter drugs and herbal supplements, you are taking.
- Avoid alcohol while taking this medicine as it may increase drowsiness.
- If you experience severe side effects, seek immediate medical attention.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Levamolin may cause drowsiness or dizziness in some individuals. Exercise caution when driving or operating machinery until you know how this medicine affects you. Avoid activities requiring mental alertness if you feel drowsy.
Lifestyle Advice
- Identify and avoid known allergy triggers such as pollen, dust mites, or certain foods.
- Maintain good indoor air quality by regularly cleaning and using air purifiers if necessary.
- Stay hydrated by drinking plenty of water.
- Avoid smoking and exposure to secondhand smoke, which can worsen allergy symptoms.
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