Marvelouse-Plus

Oral administration. Take the tablet whole with water, preferably after meals to minimize gastrointestinal discomfort.

Aceclofenac works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced prostaglandin synthesis, thereby exerting anti-inflammatory, analgesic, and antipyretic effects. Thiocolchicoside acts as a centrally acting muscle relaxant by selectively binding to GABA-A receptors and glycine receptors, producing its myorelaxant effects without sedation.

• Hypersensitivity to Aceclofenac, Thiocolchicoside, or any excipients
• Active peptic ulcer or gastrointestinal bleeding
• History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
• Severe heart failure, renal failure, or hepatic failure
• Pregnancy and lactation

Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.

Symptoms of Aceclofenac overdose may include headache, nausea, vomiting, epigastric pain, GI bleeding, rarely diarrhea, disorientation, excitation, coma, drowsiness, dizziness, tinnitus, fainting, and convulsions. Thiocolchicoside overdose symptoms are not well established but may include gastrointestinal disturbances. Management involves supportive and symptomatic treatment. Gastric lavage and activated charcoal may be considered within an hour of ingestion.

Contraindicated during pregnancy, especially in the third trimester, due to potential fetal harm (ductus arteriosus closure, renal dysfunction). Avoid during lactation as components may pass into breast milk.