Medicine Information

Optabac

Name: Optabac
Brand: Optabac
Rating: 4.5 (117 reviews)

Ophthalmic Solution (Eye Drop)0.5% w/vOphthalmic Anti-infectivesATC: S01AA12

Generic Name

optabac-05-eye-drop

Manufacturer

Square Pharmaceuticals Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
optabac 05 eye drop	৳ 34.27	N/A

Description

Overview of the medicine

Optabac-05 Eye Drop contains Tobramycin 0.5% w/v, an aminoglycoside antibiotic, used to treat bacterial infections of the external eye and its adnexa, such as conjunctivitis, blepharitis, and keratitis.

Uses & Indications

Bacterial conjunctivitis

Bacterial blepharitis

Bacterial keratitis

Other superficial ocular bacterial infections

Dosage

Adults

For mild to moderate infections: Instill 1 or 2 drops into the affected eye(s) every 4 to 6 hours. For severe infections: Instill 2 drops into the affected eye(s) every 30 to 60 minutes initially, then reduce frequency as infection is controlled.

Elderly

Same as adult dosage. No special dosage adjustment is generally required.

Renal_impairment

No dosage adjustment is necessary for topical ophthalmic use due to minimal systemic absorption.

How to Take

For topical ophthalmic use only. Tilt head back, pull down lower eyelid to create a pouch, and apply drops into the conjunctival sac. Avoid touching the dropper tip to the eye or any other surface to prevent contamination.

Mechanism of Action

Tobramycin is an aminoglycoside antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, leading to a defective bacterial cell membrane and cell death.

Pharmacokinetics

Onset

Rapid onset of action, typically within minutes to hours.

Excretion

Primarily excreted unchanged in the urine if significant systemic absorption occurs, which is rare with ophthalmic use.

Half life

Not well-defined for topical ophthalmic use due to minimal systemic absorption; systemic half-life is approximately 2-3 hours.

Absorption

Minimal systemic absorption following topical ophthalmic administration.

Metabolism

Not significantly metabolized when administered topically to the eye.

Side Effects

Contraindications

Hypersensitivity to Tobramycin or any other aminoglycoside antibiotic, or to any component of the formulation.

Drug Interactions

Other ophthalmic preparations

If using multiple ophthalmic medications, wait at least 5 minutes between applications to allow each medication to be absorbed effectively.

Storage

Store below 30°C. Protect from light. Do not freeze. Keep the bottle tightly closed when not in use. Keep out of reach of children.

Overdose

Overdose is unlikely with topical ophthalmic administration. If accidental ingestion occurs, seek medical attention. Symptomatic and supportive treatment may be necessary.

Pregnancy & Lactation

Use during pregnancy only if clearly needed and the potential benefit outweighs the potential risk to the fetus. Exercise caution when administered to a nursing woman as small amounts may be excreted in breast milk. Consult a doctor before use.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

5 ml dropper bottle10 ml dropper bottle

Shelf Life

Typically 2-3 years (unopened). Discard 28 days after opening the bottle or as advised by your pharmacist.

Availability

Available in pharmacies and hospitals

Approval Status

Approved by regulatory authorities (e.g., DGDA)

Patent Status

Generic available

WHO Essential Medicine

Yes

Clinical Trials

Clinical trials have demonstrated the efficacy and safety of Tobramycin ophthalmic solution for the treatment of bacterial ocular infections, showing significant microbial eradication and clinical improvement.

Lab Monitoring

Not typically required for topical ophthalmic use due to minimal systemic exposure.

Doctor Notes

Confirm bacterial etiology before prescribing to avoid unnecessary antibiotic use.
Educate patients on proper instillation technique to maximize efficacy and minimize contamination.
Monitor patients for signs of superinfection (e.g., fungal infection) or allergic reactions, especially with prolonged use.
Stress the importance of completing the full course of treatment.

Patient Guidelines

Wash hands thoroughly before and after applying the eye drops.
Remove contact lenses before application and wait at least 15 minutes before reinserting them.
Do not share eye drops with others to prevent cross-contamination.
Complete the full course of treatment as prescribed by your doctor, even if symptoms improve.
Avoid touching the dropper tip to any surface, including your eye.

Missed Dose Advice

If a dose is missed, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.

Driving Precautions

May cause temporary blurred vision immediately after application. Patients should be advised to avoid driving or operating machinery until their vision clears.