Povisep
Generic Name
Povidone-Iodine 10% W/W Solution
Manufacturer
ACI Limited
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| povisep 10 w solution | ৳ 55.17 | N/A |
Description
Overview of the medicine
Povisep-10-W-Solution contains Povidone-Iodine, a broad-spectrum antiseptic used for disinfecting skin, wounds, and mucous membranes. It is effective against bacteria, viruses, fungi, protozoa, and spores.
Uses & Indications
Dosage
Adults
Apply undiluted solution to the affected area as needed, usually 1-3 times daily. Allow to dry.
Elderly
No specific dosage adjustment required; use as per adult dosage.
Renal_impairment
Use with caution in severe renal impairment, especially with prolonged or extensive use, due to potential iodine absorption.
How to Take
For external use only. Apply directly to the skin or wound using a sterile swab or gauze. Do not swallow. Avoid contact with eyes.
Mechanism of Action
Povidone-iodine releases iodine, which rapidly penetrates microbial cells and oxidizes proteins, nucleotides, and fatty acids, leading to cell death. It works by non-specific, rapid destruction of microorganisms.
Pharmacokinetics
Onset
Rapid, within seconds to minutes of application.
Excretion
Systemically absorbed iodine and iodide are primarily excreted via the kidneys.
Half life
Not applicable for topical use; systemic half-life of absorbed iodine is approximately 1-2 days.
Absorption
Minimal systemic absorption through intact skin. Absorption increases with large skin areas, prolonged exposure, or damaged skin.
Metabolism
Systemically absorbed iodine is metabolized in the liver to iodide.
Side Effects
Contraindications
- Known hypersensitivity to iodine or povidone
- Thyroid disorders (e.g., hyperthyroidism, goiter) due to potential iodine absorption
- Before and after radio-iodine therapy
- In premature neonates and infants up to 6 months of age
Drug Interactions
Lithium therapy
Systemic absorption of iodine can potentiate the hypothyroid effects of lithium.
Other topical antiseptics (e.g., hydrogen peroxide, silver sulfadiazine)
May lead to inactivation of povidone-iodine or other antiseptics.
Storage
Store below 30°C in a dry place, away from direct sunlight and heat. Keep bottle tightly closed.
Overdose
Systemic overdose is unlikely with topical application. Ingestion or excessive absorption through large skin areas may lead to iodine poisoning, characterized by gastrointestinal upset, metabolic acidosis, renal impairment, and thyroid dysfunction. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Use with caution. Excessive iodine absorption could affect fetal or infant thyroid function. Consult a doctor before use, especially on large areas or for prolonged periods.
Side Effects
Contraindications
- Known hypersensitivity to iodine or povidone
- Thyroid disorders (e.g., hyperthyroidism, goiter) due to potential iodine absorption
- Before and after radio-iodine therapy
- In premature neonates and infants up to 6 months of age
Drug Interactions
Lithium therapy
Systemic absorption of iodine can potentiate the hypothyroid effects of lithium.
Other topical antiseptics (e.g., hydrogen peroxide, silver sulfadiazine)
May lead to inactivation of povidone-iodine or other antiseptics.
Storage
Store below 30°C in a dry place, away from direct sunlight and heat. Keep bottle tightly closed.
Overdose
Systemic overdose is unlikely with topical application. Ingestion or excessive absorption through large skin areas may lead to iodine poisoning, characterized by gastrointestinal upset, metabolic acidosis, renal impairment, and thyroid dysfunction. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Use with caution. Excessive iodine absorption could affect fetal or infant thyroid function. Consult a doctor before use, especially on large areas or for prolonged periods.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date, check specific product label.
Availability
Pharmacies, hospitals, clinics, general stores
Approval Status
Approved by health authorities worldwide for over-the-counter use.
Patent Status
Generic (original patent expired)
WHO Essential Medicine
YesClinical Trials
Povidone-iodine has been extensively studied in numerous clinical trials demonstrating its efficacy as a broad-spectrum antiseptic for various indications including surgical site preparation, wound management, and mucous membrane disinfection.
Lab Monitoring
- Thyroid function tests (TFTs) if used extensively, for prolonged periods, or in at-risk individuals (e.g., neonates, patients with pre-existing thyroid conditions).
Doctor Notes
- Emphasize topical use only and caution against ingestion.
- Advise patients to report any signs of hypersensitivity or irritation immediately.
- Monitor thyroid function in patients with extensive or prolonged use, or pre-existing thyroid conditions.
Patient Guidelines
- Do not use for more than 7 days without consulting a doctor.
- If irritation or rash develops, discontinue use and consult a healthcare professional.
- Keep out of reach of children.
- Avoid contact with eyes; if contact occurs, rinse thoroughly with water.
Missed Dose Advice
As this is an on-demand topical application, there is no concept of a 'missed dose'. Apply as needed when required for antisepsis.
Driving Precautions
Does not affect ability to drive or operate machinery.
Lifestyle Advice
- Maintain good hygiene to prevent infections.
- Keep wounds clean and covered after antisepsis.
- Proper wound care is essential for healing.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Povisep Brand
Other medicines available under the same brand name
Povisep
Vaginal Gel
Povisep
Solution (Topical Antiseptic)
Povisep
Cream
Povisep
Surgical Scrub Solution
Povisep
Mouthwash
Povisep
Eye Drop
Povisep
Powder