Medicine Information

Airup

Name: Airup
Brand: Airup
Rating: 4.5 (117 reviews)

Tablet10 mgLeukotriene Receptor AntagonistATC: R03DC03

Generic Name

Montelukast

Manufacturer

Medivest Pharmaceuticals Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
airup 10 mg tablet	৳ 16.00	৳ 240.00

Description

Overview of the medicine

Airup 10 mg Tablet contains Montelukast, a leukotriene receptor antagonist. It is used to prevent and treat chronic asthma, exercise-induced bronchoconstriction, and allergic rhinitis.

Uses & Indications

Prophylaxis and chronic treatment of asthma

Prevention of exercise-induced bronchoconstriction

Relief of symptoms of seasonal and perennial allergic rhinitis

Dosage

Adults

10 mg orally once daily in the evening.

Elderly

No dosage adjustment required.

Renal_impairment

No dosage adjustment required.

How to Take

Take orally once daily in the evening, with or without food.

Mechanism of Action

Montelukast selectively antagonizes the CysLT1 receptor, thereby blocking the actions of leukotrienes, which are potent inflammatory mediators involved in asthma and allergic rhinitis. This leads to bronchodilation and reduction of inflammation.

Pharmacokinetics

Onset

Within 1-2 hours

Excretion

Primarily excreted in feces via bile.

Half life

2.7-5.5 hours

Absorption

Rapidly absorbed after oral administration, peak plasma concentration reached in 2-4 hours.

Metabolism

Extensively metabolized by CYP3A4, 2C8, and 2C9 in the liver.

Side Effects

Contraindications

Hypersensitivity to Montelukast or any component of the formulation
Acute asthma attacks (not for rescue use)

Drug Interactions

Rifampin

May decrease Montelukast plasma concentrations.

Phenobarbital

May decrease Montelukast plasma concentrations.

Storage

Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.

Overdose

Symptoms include abdominal pain, somnolence, thirst, headache, vomiting, and psychomotor hyperactivity. Treatment is symptomatic and supportive.

Pregnancy & Lactation

Pregnancy Category B. Use during pregnancy only if clearly needed. Excreted in breast milk, caution advised during lactation.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

10 tablets30 tablets

Shelf Life

24 months

Availability

Available in pharmacies nationwide

Approval Status

Approved by DGDA

Patent Status

Patent expired, available as generic

Clinical Trials

Montelukast has been extensively studied in numerous clinical trials demonstrating its efficacy and safety in asthma and allergic rhinitis.

Lab Monitoring

No routine laboratory monitoring is typically required.

Doctor Notes

Emphasize to patients that Montelukast is not for acute symptom relief.
Monitor for neuropsychiatric symptoms, especially in pediatric patients.
Advise patients on proper adherence for optimal therapeutic benefit.

Patient Guidelines

Do not stop taking the medicine suddenly without consulting your doctor.
This medicine is for long-term control, not for acute asthma attacks.
Report any mood changes or behavioral disturbances to your doctor immediately.

Missed Dose Advice

If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Driving Precautions

May cause dizziness or somnolence. Patients should be cautious when driving or operating machinery until they know how Airup affects them.

Lifestyle Advice

Avoid triggers that worsen your asthma or allergies (e.g., dust, pollen, pet dander).
Maintain a healthy lifestyle with regular exercise (as tolerated) and a balanced diet.