Medicine Information

Arthrosin

Name: Arthrosin
Brand: Arthrosin
Rating: 4.5 (117 reviews)

Tablet250 mgJoint Care, Osteoarthritis ManagementATC: M01AX05

Generic Name

Glucosamine Sulfate

Manufacturer

Popular Pharmaceuticals Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
arthrosin 250 mg tablet	৳ 8.50	৳ 85.00

Description

Overview of the medicine

Arthrosin 250 mg Tablet contains Glucosamine Sulfate, a natural compound found in cartilage. It is used to help build and repair cartilage, alleviate joint pain, and improve mobility in conditions like osteoarthritis.

Uses & Indications

Relief of symptoms in mild to moderate osteoarthritis

Improvement of joint mobility and flexibility

Support for healthy cartilage and joint function

Dosage

Adults

Oral, 1-2 tablets (250-500 mg) three times daily, or as directed by physician. Effects may take several weeks to appear.

Elderly

No specific dose adjustment required for elderly patients, same as adult dose.

Renal_impairment

Use with caution in severe renal impairment; no specific dose adjustment guidelines are established. Consult a physician.

How to Take

Take tablets orally with water, preferably with meals to minimize gastrointestinal discomfort.

Mechanism of Action

Glucosamine is a precursor for glycosaminoglycans, a major component of cartilage. It stimulates the synthesis of proteoglycans and collagen, which are essential for maintaining cartilage structure and function. It may also have anti-inflammatory effects.

Pharmacokinetics

Onset

Therapeutic effects typically observed after 2-4 weeks of continuous use.

Excretion

Mainly via urine (up to 10%) and feces (up to 11%), with a significant portion being incorporated into tissues.

Half life

Approximately 15-18 hours.

Absorption

Approximately 90% oral absorption, with systemic bioavailability ranging from 25-26% due to first-pass metabolism.

Metabolism

Primarily metabolized in the liver to smaller molecules, including amino acids, and some non-metabolized portion passes through.

Side Effects

Contraindications

Hypersensitivity to Glucosamine Sulfate or any excipients
Allergy to shellfish (if derived from shellfish)
Pregnancy and lactation (lack of sufficient data)

Drug Interactions

Antidiabetic drugs

Glucosamine may affect glucose metabolism. Monitor blood glucose levels, especially in diabetic patients.

Tetracycline antibiotics

May increase the absorption of tetracycline.

Warfarin and other anticoagulants

May increase the anticoagulant effect, leading to an increased risk of bleeding. Monitor INR carefully.

Storage

Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.

Overdose

High doses may cause gastrointestinal discomfort (nausea, vomiting, diarrhea). Treatment is symptomatic and supportive.

Pregnancy & Lactation

Not recommended during pregnancy and lactation due to insufficient data on safety. Consult a doctor.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

30 tablets (3x10's)

Shelf Life

36 months from manufacturing date

Availability

Pharmacies, health stores, online

Approval Status

Available as a dietary supplement/OTC drug in many regions

Patent Status

Generic

Clinical Trials

Numerous clinical trials have investigated the efficacy of glucosamine sulfate in osteoarthritis, with mixed results. Some studies show modest benefits in pain and function, while others do not find significant differences compared to placebo. Efficacy may vary based on formulation and severity of osteoarthritis.

Lab Monitoring

Blood glucose levels in diabetic patients
INR in patients taking anticoagulants

Doctor Notes

Advise patients that effects are not immediate and require consistent use for several weeks.
Counsel diabetic patients about potential blood glucose monitoring.
Enquire about shellfish allergy before prescribing/recommending.

Patient Guidelines

Take consistently for optimal results, as effects may take time to appear.
Inform your doctor about all other medications you are taking.
Do not exceed the recommended dose.

Missed Dose Advice

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.

Driving Precautions

Generally, Arthrosin is not expected to affect the ability to drive or operate machinery. However, if you experience dizziness or drowsiness, avoid such activities.