Medicine Information

Bronsol

Name: Bronsol
Brand: Bronsol
Rating: 4.5 (117 reviews)

Syrup15 mg/5 mlMucolytic and ExpectorantATC: R05CB06

Generic Name

Ambroxol Hydrochloride

Manufacturer

Square Pharmaceuticals Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
bronsol 15 mg syrup	৳ 42.00	N/A

Description

Overview of the medicine

Bronsol 15 mg Syrup contains Ambroxol Hydrochloride, a mucolytic agent used to thin and loosen mucus in the airways, making it easier to cough up. It is commonly prescribed for respiratory conditions associated with excessive mucus production.

Uses & Indications

Acute and chronic broncho-pulmonary diseases associated with abnormal mucus secretion and impaired mucus transport

Acute exacerbations of chronic bronchitis

Asthmatic bronchitis

Bronchial asthma with difficulty in expectoration

Dosage

Adults

Typically 30 mg (10 ml of 15 mg/5 ml syrup) 2-3 times daily, or as directed by physician.

Elderly

No specific dose adjustment required, but caution is advised in patients with severe renal or hepatic impairment.

Renal_impairment

Dose interval may need to be extended in severe renal impairment.

How to Take

Oral administration. May be taken with or without food. Use a measuring spoon or cup provided to ensure accurate dosage.

Mechanism of Action

Ambroxol acts as a mucolytic by depolymerizing mucopolysaccharides, thereby reducing the viscosity of bronchial secretions. It also stimulates the synthesis and secretion of pulmonary surfactant, which plays a critical role in pulmonary defense mechanisms.

Pharmacokinetics

Onset

30 minutes to 1 hour (mucolytic effect)

Excretion

Mainly excreted renally (about 90%) as metabolites, with a small portion unchanged.

Half life

Approximately 7-12 hours (terminal half-life)

Absorption

Rapidly and almost completely absorbed after oral administration. Peak plasma concentrations are reached within 1-2.5 hours.

Metabolism

Primarily metabolized in the liver to inactive metabolites via first-pass metabolism.

Side Effects

Contraindications

Hypersensitivity to Ambroxol or any component of the syrup
Rare hereditary conditions that may be incompatible with an excipient of the product (e.g., fructose intolerance for syrups containing sorbitol)

Drug Interactions

Cough suppressants

Concomitant use with antitussives may lead to a dangerous accumulation of secretions due to the inhibition of the cough reflex. Avoid co-administration.

Antibiotics (e.g., amoxicillin, cefuroxime, erythromycin, doxycycline)

Ambroxol can increase the penetration of these antibiotics into bronchial secretions, potentially enhancing their therapeutic effect.

Storage

Store below 30°C in a dry place, away from light. Keep out of reach of children. Do not freeze.

Overdose

Symptoms: Nausea, vomiting, diarrhea, indigestion. Management: Symptomatic and supportive treatment. Induce emesis or perform gastric lavage if overdose is recent and massive. Monitor vital signs.

Pregnancy & Lactation

Pregnancy Category C. Use during pregnancy, especially in the first trimester, should be avoided unless the benefits outweigh the risks. Excreted in breast milk, so use with caution during lactation or avoid if possible.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

100 ml syrup200 ml syrup

Shelf Life

Typically 2-3 years from manufacturing date when stored correctly.

Availability

Pharmacies, hospitals, clinics worldwide

Approval Status

Approved by drug regulatory authorities worldwide

Patent Status

Generic available (patent expired)

WHO Essential Medicine

Yes

Clinical Trials

Numerous clinical trials have demonstrated Ambroxol's efficacy in improving mucociliary clearance and reducing symptoms in various respiratory conditions, including acute and chronic bronchitis.

Lab Monitoring

No specific routine lab monitoring is required.
Monitor renal and hepatic function in patients with pre-existing impairment if treatment is prolonged.

Doctor Notes

Advise patients to drink plenty of water to augment mucolytic effect.
Be aware of potential drug interactions with antitussives.
Caution in patients with a history of severe allergic skin reactions.

Patient Guidelines

Do not exceed the recommended dose.
Shake the bottle well before use.
Complete the full course of treatment as prescribed, even if symptoms improve.
Consult a doctor if symptoms persist or worsen.

Missed Dose Advice

If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.

Driving Precautions

Ambroxol is generally not expected to affect the ability to drive or operate machinery. However, if side effects like dizziness occur, avoid such activities.

Lifestyle Advice

Maintain adequate hydration by drinking plenty of fluids to help thin mucus.
Avoid smoking and exposure to irritants that can worsen respiratory conditions.

Alternative Medicines in Bangladesh

Similar medicines available in the market

Mekofex (Renata Limited)Ambrox (Beximco Pharmaceuticals)Broncholyt (Incepta Pharmaceuticals)

Global Brand Names

International brand names for this medicine

MediCore Pharmaceuticals Ltd.

Tablet100 mg

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