Medicine Information

Caridol

Name: Caridol
Brand: Caridol
Rating: 4.5 (117 reviews)

Tablet250 mgSkeletal Muscle RelaxantsATC: M03BA02

Generic Name

Carisoprodol

Manufacturer

Eskayef Pharmaceuticals Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
caridol 250 mg tablet	৳ 7.00	৳ 70.00

Description

Overview of the medicine

Caridol 250 mg Tablet contains Carisoprodol, a centrally acting skeletal muscle relaxant used for the relief of discomfort associated with acute, painful musculoskeletal conditions.

Uses & Indications

For the relief of discomfort associated with acute, painful musculoskeletal conditions.

Used as an adjunct to rest, physical therapy, and other measures for the relief of pain.

Dosage

Adults

250 mg to 350 mg three times daily and at bedtime. Maximum recommended duration of use is two to three weeks.

Elderly

Lower doses may be required; use with caution due to increased risk of side effects.

Renal_impairment

Use with caution. Dosage adjustment may be necessary in severe renal impairment.

How to Take

Take orally, with or without food. It can be taken with food to reduce stomach upset.

Mechanism of Action

Carisoprodol works by blocking interneuronal activity in the descending reticular formation and spinal cord, resulting in skeletal muscle relaxation. Its mechanism is not fully understood but involves general central nervous system depression.

Pharmacokinetics

Onset

Within 30 minutes.

Excretion

Mainly excreted by the kidneys (urine) as meprobamate and other metabolites.

Half life

Carisoprodol: approximately 8 hours; Meprobamate (active metabolite): approximately 2-3 hours.

Absorption

Rapidly absorbed from the gastrointestinal tract.

Metabolism

Extensively metabolized in the liver by cytochrome P450 enzyme CYP2C19 to form meprobamate, an active metabolite.

Side Effects

Contraindications

Hypersensitivity to carisoprodol, meprobamate, or any component of the formulation.
Acute intermittent porphyria.

Drug Interactions

Alcohol

Increased central nervous system (CNS) depressant effects.

CYP2C19 inhibitors/inducers

May alter carisoprodol metabolism and plasma concentrations.

CNS Depressants (e.g., benzodiazepines, opioids, sedatives, hypnotics)

Additive CNS depressant effects, increasing the risk of sedation, respiratory depression, and hypotension.

Storage

Store in a cool, dry place below 25°C. Protect from moisture and light. Keep out of reach of children.

Overdose

Symptoms may include CNS depression (e.g., stupor, coma, shock), respiratory depression, seizures, and hypotension. Management is primarily supportive, including gastric lavage, activated charcoal, and symptomatic treatment.

Pregnancy & Lactation

Pregnancy Category C. Carisoprodol is excreted in breast milk. Not recommended during pregnancy or lactation unless the benefits outweigh the risks.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

10 tablets per strip30 tablets per box

Shelf Life

Typically 2-3 years from the date of manufacture, check product packaging for exact date.

Availability

Available in pharmacies nationwide

Approval Status

Approved

Patent Status

Generic

Clinical Trials

Carisoprodol has undergone clinical trials to establish its efficacy and safety in the management of acute musculoskeletal pain. Studies have demonstrated its ability to reduce pain and improve mobility.

Lab Monitoring

Liver and kidney function tests may be considered with prolonged use, especially in patients with pre-existing impairment.

Doctor Notes

Educate patients on the short-term nature of treatment and the risks of dependence and withdrawal.
Caution patients about additive CNS depressant effects with alcohol and other sedatives.
Monitor for signs of CNS depression, especially in elderly patients or those with hepatic/renal impairment.

Patient Guidelines

Avoid activities requiring mental alertness, such as driving or operating machinery, as this medicine can cause drowsiness and dizziness.
Avoid alcohol and other CNS depressants while taking Caridol.
Do not stop taking this medicine abruptly without consulting your doctor, as withdrawal symptoms may occur.
The duration of use should generally be limited to two to three weeks for acute conditions.

Missed Dose Advice

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Driving Precautions

Caridol can cause drowsiness and dizziness, which may impair your ability to drive or operate heavy machinery. Avoid these activities until you know how the medicine affects you.

Lifestyle Advice

Combine Caridol with rest, physical therapy, and other non-pharmacological interventions for optimal pain relief.
Maintain good posture and engage in gentle stretching exercises as advised by your healthcare provider.