Medicine Information

Ciprox

Name: Ciprox
Brand: Ciprox
Rating: 4.5 (117 reviews)

Eye Ointment0.3% w/vOphthalmic AntibioticsATC: S01AX13

Generic Name

Ciprofloxacin 0.3% Eye Ointment

Manufacturer

Acme Pharma Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
ciprox 03 eye ointment	৳ 35.00	N/A

Description

Overview of the medicine

Ciprofloxacin 0.3% Eye Ointment is an antibiotic medication used to treat bacterial infections of the eye, such as conjunctivitis and corneal ulcers. It works by stopping the growth of bacteria.

Uses & Indications

Bacterial conjunctivitis

Corneal ulcers

Bacterial blepharitis

Prophylaxis after ocular surgery

Dosage

Adults

For bacterial conjunctivitis: Apply a small amount (about 1/2 inch ribbon) into the conjunctival sac of the affected eye(s) three times daily for 7-14 days. For corneal ulcers: Apply a 1/2 inch ribbon into the conjunctival sac every 1-2 hours for the first 2 days, then every 4 hours for the next 5 days, and then 3 times a day for 7-14 days.

Elderly

Same as adult dosage. No specific dosage adjustment is necessary.

Renal_impairment

No dosage adjustment required for ophthalmic use as systemic absorption is minimal.

How to Take

Wash hands thoroughly before use. Tilt head back, pull down the lower eyelid to form a pouch. Squeeze a small amount (about 1/2 inch) of ointment into the pouch. Close the eye gently for 1-2 minutes. Avoid touching the tip of the tube to the eye or any other surface to prevent contamination.

Mechanism of Action

Ciprofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. This leads to cell death.

Pharmacokinetics

Onset

Rapid, within hours of initial application.

Excretion

Primarily via urine if systemically absorbed; local excretion not significant.

Half life

Not clinically relevant for local ophthalmic use; systemic half-life is 3-5 hours if absorbed.

Absorption

Minimal systemic absorption from ophthalmic administration; peak concentrations are achieved rapidly in ocular tissues.

Metabolism

Minimally metabolized in the eye. If systemically absorbed, it is partially metabolized in the liver.

Side Effects

Contraindications

Hypersensitivity to ciprofloxacin or any other fluoroquinolone
Hypersensitivity to any component of the ointment

Drug Interactions

Other ophthalmic medications

Systemic drug interactions are unlikely due to minimal absorption. If using other ophthalmic medications, wait at least 5-10 minutes between applications to prevent washout.

Storage

Store below 25°C. Protect from light and moisture. Do not freeze. Keep out of reach of children.

Overdose

Ophthalmic overdose is unlikely to cause systemic toxicity due to limited absorption. If accidentally swallowed, supportive measures may be considered, but severe toxicity is rare.

Pregnancy & Lactation

Use during pregnancy and lactation is generally considered safe due to minimal systemic absorption; however, consult a doctor before use. Limited human data suggest no increased risk of major birth defects.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

3.5 g tube

Shelf Life

2-3 years (unopened); 28 days after opening (discard after this period).

Availability

Available in pharmacies and hospitals

Approval Status

Approved by regulatory authorities

Patent Status

Generically available

WHO Essential Medicine

Yes

Clinical Trials

Numerous clinical trials have demonstrated the efficacy and safety of ciprofloxacin ophthalmic ointment for treating bacterial conjunctivitis and corneal ulcers caused by susceptible organisms, showing significant bacterial eradication rates and clinical improvement.

Lab Monitoring

Not generally required for ophthalmic use due to minimal systemic exposure.

Doctor Notes

Emphasize proper application technique to patients to avoid contamination and maximize efficacy.
Advise patients not to share eye medications to prevent cross-contamination.
Monitor for signs of secondary infection (e.g., fungal) or allergic reactions, and discontinue if they occur.
Educate on the importance of completing the full prescribed course of treatment.

Patient Guidelines

Do not wear contact lenses during treatment for bacterial eye infections.
Wash hands thoroughly before and after application to prevent contamination.
Avoid contaminating the tip of the tube by not touching it to the eye or any other surface.
Complete the full course of treatment even if symptoms improve.
Consult a doctor if symptoms worsen or do not improve within a few days.

Missed Dose Advice

If a dose is missed, apply it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.

Driving Precautions

May cause temporary blurred vision or discomfort immediately after application. Avoid driving or operating machinery until vision clears and any discomfort subsides.