Medicine Information

Cold-B

Name: Cold-B
Brand: Cold-B
Rating: 4.5 (117 reviews)

Tablet4 mgAntihistamineATC: R06AB04

Generic Name

Chlorpheniramine Maleate

Manufacturer

Hypothetical Pharma Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
cold b 4 mg tablet	৳ 0.70	N/A

Description

Overview of the medicine

Cold-B 4 mg Tablet contains Chlorpheniramine Maleate, a first-generation antihistamine used to relieve symptoms of allergies like sneezing, runny nose, watery eyes, and itching. It can also help with common cold symptoms.

Uses & Indications

Symptomatic relief of allergic conditions

Seasonal allergic rhinitis (hay fever)

Perennial allergic rhinitis

Vasomotor rhinitis

Allergic conjunctivitis

Urticaria

Angioedema

Pruritus

Adjunct in anaphylactic reactions

Dosage

Adults

1 tablet (4 mg) every 4-6 hours. Maximum 6 tablets (24 mg) in 24 hours.

Elderly

Lower doses may be required due to increased sensitivity to side effects. Consult a doctor.

Renal_impairment

Use with caution; dose reduction may be necessary. Consult a doctor.

How to Take

Oral. Can be taken with or without food.

Mechanism of Action

Chlorpheniramine Maleate is a first-generation antihistamine that works by blocking histamine H1 receptors. This prevents histamine, a chemical released during allergic reactions, from binding to its receptors and causing symptoms.

Pharmacokinetics

Onset

30-60 minutes.

Excretion

Excreted primarily in urine as metabolites and unchanged drug.

Half life

12-43 hours (variable).

Absorption

Well absorbed from the gastrointestinal tract.

Metabolism

Extensively metabolized in the liver.

Side Effects

Contraindications

Hypersensitivity to chlorpheniramine or any component of the formulation
Newborns or premature infants
During an acute asthmatic attack
In combination with MAO inhibitors

Drug Interactions

MAO Inhibitors

Increased and prolonged anticholinergic effects.

Anticholinergics

Enhanced anticholinergic effects (e.g., dry mouth, blurred vision).

CNS Depressants (alcohol, sedatives, tranquilizers)

Increased sedation.

Storage

Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.

Overdose

Symptoms include drowsiness, central nervous system depression (sedation, coma), or excitation (insomnia, hallucinations, convulsions). Management is supportive and symptomatic, including gastric lavage or activated charcoal if recent ingestion.

Pregnancy & Lactation

Use with caution. Consult a doctor. Generally not recommended in the third trimester of pregnancy or during breastfeeding due to potential for adverse effects on fetus/infant.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

10 tablets (blister)20 tablets (blister)

Shelf Life

Typically 2-3 years from manufacturing date.

Availability

Pharmacies, drugstores

Approval Status

Approved by regulatory authorities

Patent Status

Off-patent

WHO Essential Medicine

Yes

Clinical Trials

Extensively studied and widely used for decades. New trials focus on specific populations or formulations.

Lab Monitoring

Liver function tests (in prolonged use or in patients with liver impairment)
Renal function tests (in prolonged use or in patients with renal impairment)

Doctor Notes

Advise patients about potential drowsiness.
Caution in elderly, prostate hypertrophy, narrow-angle glaucoma.
Review concurrent medications for interactions, especially CNS depressants and MAOIs.

Patient Guidelines

Do not exceed the recommended dose.
Avoid driving or operating machinery if drowsiness occurs.
Avoid alcohol while taking this medicine.
Inform your doctor about all other medications you are taking.

Missed Dose Advice

If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Driving Precautions

May cause drowsiness and impair ability to drive or operate machinery. Exercise caution.

Lifestyle Advice

Stay hydrated.
Avoid known allergens where possible.
Get adequate rest.

Alternative Medicines in Bangladesh

Similar medicines available in the market

Histacin (Square Pharmaceuticals)Anti-A (Beximco Pharmaceuticals)Cofen (Incepta Pharmaceuticals)

Global Brand Names

International brand names for this medicine

Incepta Pharmaceuticals Ltd.

Tablet60 mg, 90 mg, 120 mg

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