Medicine Information

Famisus

Name: Famisus
Brand: Famisus
Rating: 4.5 (117 reviews)

Oral Suspension40 mg/5 mlAntacid, Anti-Reflux & Anti-UlcerantATC: A02BA03

Generic Name

Famotidine

Manufacturer

Acme Pharmaceuticals

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
famisus 40 mg suspension	৳ 48.00	N/A

Description

Overview of the medicine

Famisus 40 mg Suspension is used to treat and prevent ulcers in the stomach and intestines. It is also used to treat conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome, and to treat gastroesophageal reflux disease (GERD).

Uses & Indications

Duodenal ulcer

Gastric ulcer

Gastroesophageal Reflux Disease (GERD)

Zollinger-Ellison syndrome

Pathological hypersecretory conditions

Dosage

Adults

For active duodenal ulcer: 40 mg once daily at bedtime for 4-8 weeks. For GERD: 20-40 mg twice daily for 6-12 weeks. For pathological hypersecretory conditions: 20-160 mg every 6 hours.

Elderly

No specific dose adjustment is generally required, but caution in severe renal impairment.

Renal_impairment

Dose reduction (e.g., 20 mg once daily or every other day) is recommended for creatinine clearance <10 mL/min.

How to Take

Shake well before use. May be taken with or without food. Use a measuring device for accurate dosing.

Mechanism of Action

Famotidine is a histamine H2-receptor antagonist that inhibits gastric acid secretion by blocking the action of histamine on H2 receptors on the parietal cells of the stomach.

Pharmacokinetics

Onset

Within 1 hour

Excretion

Primarily excreted in the urine (65-70% as unchanged drug).

Half life

2.5-3.5 hours

Absorption

Rapidly absorbed after oral administration. Bioavailability is approximately 40-45%.

Metabolism

Partially metabolized in the liver to an inactive sulfoxide metabolite.

Side Effects

Contraindications

Hypersensitivity to famotidine or other H2-receptor antagonists
Acute porphyria

Drug Interactions

Antacids

May decrease absorption of famotidine. Take famotidine 1-2 hours before or after antacids.

Cefpodoxime proxetil

Reduced absorption due to gastric pH changes.

Ketoconazole/Itraconazole

Famotidine can decrease the absorption of these drugs due to increased gastric pH. Administer several hours apart.

Storage

Store below 30°C in a dry place, away from light. Do not freeze.

Overdose

Symptoms may include hypotension, tachycardia, vomiting, and diarrhea. Management includes symptomatic and supportive therapy.

Pregnancy & Lactation

Pregnancy Category B. Use only if clearly needed. Famotidine is excreted in breast milk; caution should be exercised.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

50 ml suspension100 ml suspension

Shelf Life

24 months

Availability

Pharmacies, hospitals

Approval Status

Approved

Patent Status

Expired

WHO Essential Medicine

Yes

Clinical Trials

Extensive clinical trials have established the efficacy and safety of famotidine for its indicated uses.

Lab Monitoring

No routine lab monitoring is generally required. Monitor liver and renal function in patients with pre-existing impairment or long-term therapy.

Doctor Notes

Advise patients about potential rebound acid secretion upon discontinuation.
Consider dose adjustment in patients with significant renal impairment.

Patient Guidelines

Complete the full course of treatment as prescribed.
Do not stop taking the medicine suddenly without consulting your doctor.
Inform your doctor if symptoms do not improve or worsen.

Missed Dose Advice

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.

Driving Precautions

May cause dizziness or fatigue. If affected, avoid driving or operating heavy machinery.

Lifestyle Advice

Avoid spicy and fatty foods, caffeine, and alcohol to reduce acid reflux.
Elevate the head of your bed to prevent nighttime reflux.
Quit smoking as it can worsen symptoms.

Alternative Medicines in Bangladesh

Similar medicines available in the market

Famo (Square)Famtac (Incepta)Famoson (Beximco)

Global Brand Names

International brand names for this medicine

MediCore Pharmaceuticals Ltd.

Tablet100 mg

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