Medicine Information

Flomox

Name: Flomox
Brand: Flomox
Rating: 4.5 (117 reviews)

Eye Drop0.5% (w/v)Ophthalmic Antibiotics, FluoroquinolonesATC: S01AE07

Generic Name

Moxifloxacin Ophthalmic Solution

Manufacturer

Healthcare Pharmaceuticals Ltd.

Country

Bangladesh

Loading images...

Price Details

Current market pricing information

Variant	Unit Price	Strip Price
flomox 05 eye drop	৳ 140.00	N/A

Description

Overview of the medicine

Flomox-05 Eye Drop contains Moxifloxacin, a fourth-generation fluoroquinolone antibiotic, used to treat bacterial conjunctivitis and other superficial ocular infections caused by susceptible organisms. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication and repair.

Uses & Indications

Treatment of bacterial conjunctivitis

Treatment of other superficial ocular infections caused by susceptible strains

Prophylaxis before and after ocular surgery

Dosage

Adults

Instill one drop in the affected eye(s) 3 times daily for 7 days, or as directed by a physician.

Elderly

No dosage adjustment necessary.

Renal_impairment

No dosage adjustment necessary.

How to Take

For ophthalmic use only. Tilt head back, pull down the lower eyelid to form a pouch, instill the drop, and close the eye gently. Do not touch the dropper tip to any surface.

Mechanism of Action

Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. This leads to bacterial cell death.

Pharmacokinetics

Onset

Rapid onset of action, typically within hours for symptom relief.

Excretion

Mainly renal and fecal excretion for systemically absorbed drug; minimal for topical ocular application.

Half life

Not precisely defined for topical ocular use due to minimal systemic absorption; systemic half-life is approximately 12 hours.

Absorption

Minimal systemic absorption following topical ocular administration. Local absorption into ocular tissues is good.

Metabolism

Minimal systemic metabolism after topical ocular administration; primarily hepatic for systemically absorbed drug.

Side Effects

Contraindications

Hypersensitivity to moxifloxacin or any other fluoroquinolone
Hypersensitivity to any component of the formulation

Drug Interactions

Systemic corticosteroids

Increased risk of tendon rupture with systemic fluoroquinolones, but unlikely with topical ophthalmic use due to minimal systemic absorption.

Storage

Store at room temperature (15°C-30°C). Protect from light and moisture. Do not freeze. Keep the bottle tightly closed when not in use.

Overdose

Due to minimal systemic absorption following topical ophthalmic administration, an overdose is unlikely. If excessive drops are applied, flush the eye with lukewarm water.

Pregnancy & Lactation

Use during pregnancy only if clearly needed and the potential benefit outweighs the potential risk to the fetus. Exercise caution when administered to a nursing mother. Consult a physician.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

5 mL bottle

Shelf Life

Typically 2-3 years unopened; 28 days after opening.

Availability

Pharmacies, Hospitals

Approval Status

Approved by major regulatory bodies (e.g., FDA, DGDA)

Patent Status

Generics available, patent expired for original compound

Clinical Trials

Moxifloxacin ophthalmic solutions have demonstrated efficacy and safety in multiple randomized, double-masked clinical trials for the treatment of bacterial conjunctivitis.

Lab Monitoring

Not typically required for topical ophthalmic moxifloxacin due to minimal systemic absorption.

Doctor Notes

Advise patients to complete the full course of therapy.
Counsel on proper administration technique to avoid contamination and maximize efficacy.
Remind patients not to wear contact lenses during treatment.

Patient Guidelines

Wash hands before and after use.
Do not wear contact lenses during treatment with eye drops unless advised by a doctor.
Discard the bottle 28 days after opening, even if some solution remains.
Complete the full course of treatment as prescribed by your doctor, even if symptoms improve.

Missed Dose Advice

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not apply a double dose to make up for a missed one.