Medicine Information

Floximox

Name: Floximox
Brand: Floximox
Rating: 4.5 (117 reviews)

Eye Drop0.5% (w/v)Ophthalmic Anti-infectivesATC: S01AE07

Generic Name

Floximox Ophthalmic Solution 0.5%

Manufacturer

Hypothetical Pharma Inc.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
floximox 05 eye drop	৳ 100.00	N/A

Description

Overview of the medicine

Floximox-05 Eye Drop contains Floximox, a broad-spectrum fluoroquinolone antibiotic, indicated for the treatment of bacterial conjunctivitis and other susceptible ocular infections.

Uses & Indications

Bacterial conjunctivitis

Corneal ulcers

Other superficial ocular infections caused by susceptible organisms

Dosage

Adults

Instill 1 drop into the affected eye(s) 3 times daily for 7 days.

Elderly

No specific dose adjustment required for elderly patients.

Renal_impairment

Not applicable for ophthalmic administration due to minimal systemic absorption.

How to Take

For ophthalmic use only. Wash hands thoroughly before administration. Do not allow the dropper tip to touch the eye or any other surface to prevent contamination. Tilt head back, pull down the lower eyelid to form a pocket, and instill one drop into the conjunctival sac. Close eye gently and apply light pressure to the inner corner of the eye for 1-2 minutes to minimize systemic absorption.

Mechanism of Action

Floximox inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination, leading to bacterial cell death.

Pharmacokinetics

Onset

Rapid onset of action, typically within hours for symptomatic relief.

Excretion

Primarily excreted via the tear film and ocular surface with minimal systemic elimination.

Half life

Not well characterized systemically due to minimal absorption; local ocular half-life varies.

Absorption

Minimal systemic absorption after ocular administration. High concentrations achieved in tear film and ocular tissues.

Metabolism

Limited systemic metabolism; predominantly excreted unchanged via ocular routes.

Side Effects

Contraindications

Hypersensitivity to Floximox or other quinolones
Viral or fungal eye infections

Drug Interactions

General

No significant interactions expected with ophthalmic administration due to minimal systemic absorption.

Storage

Store at room temperature (15-30°C). Protect from light and moisture. Do not freeze. Keep the bottle tightly closed when not in use. Keep out of reach of children.

Overdose

Overdose is highly unlikely with ocular administration. In case of accidental ingestion or excessive ocular exposure, the eye may be flushed with lukewarm water. Symptomatic treatment is generally sufficient. If irritation persists, seek medical advice.

Pregnancy & Lactation

Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution should be exercised when administered to a nursing mother. Consult a doctor.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

5 mL bottle

Shelf Life

24 months (unopened). Discard 28 days after first opening.

Availability

Pharmacies, Hospitals

Approval Status

Approved

Patent Status

Patent Expired

Clinical Trials

Extensive phase III clinical trials have demonstrated Floximox-05's efficacy and safety in the treatment of bacterial conjunctivitis, showing significant bacterial eradication and clinical cure rates compared to placebo and active comparators.

Lab Monitoring

Not typically required for ophthalmic Floximox-05.

Doctor Notes

Advise patients on proper administration technique.
Emphasize completing the full course of therapy.
Monitor for signs of superinfection.
Patients should report any persistent irritation or new symptoms.

Patient Guidelines

Do not wear contact lenses during treatment.
Avoid contaminating the dropper tip.
Complete the full course of treatment even if symptoms improve.
Discontinue use and consult a doctor if superinfection occurs.

Missed Dose Advice

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not apply a double dose to make up for a missed one.

Driving Precautions

Floximox-05 Eye Drop may cause temporary blurred vision or other visual disturbances. If this occurs, patients should be advised to refrain from driving or operating machinery until their vision clears.