Medicine Information

Fluroid-G

Name: Fluroid-G
Brand: Fluroid-G
Rating: 4.5 (117 reviews)

SuspensionFluocinolone Acetonide 0.01% w/v + Gentamicin Sulfate 0.3% w/vCorticosteroid & Antibiotic Combination (Ophthalmic/Otic)ATC: S01CA

Generic Name

Fluocinolone Acetonide + Gentamicin Sulfate

Manufacturer

Apotex Inc.

Country

Canada

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
fluroid g 01 03 suspension	৳ 110.00	N/A

Description

Overview of the medicine

Fluroid-G-01-03 Suspension is an ophthalmic or otic suspension containing a combination of a corticosteroid (Fluocinolone Acetonide) and an aminoglycoside antibiotic (Gentamicin Sulfate) used to treat inflammatory and infectious conditions of the eye or ear.

Uses & Indications

Bacterial conjunctivitis with inflammation

Bacterial blepharitis with inflammation

Otitis externa with inflammation

Other susceptible ocular or otic infections where corticosteroid is indicated to reduce inflammation.

Dosage

Adults

1-2 drops into the affected eye/ear 2-4 times daily, or as directed by physician.

Elderly

No specific dosage adjustment required, but monitor for systemic absorption if prolonged use.

Renal_impairment

Systemic absorption is minimal, so no specific adjustment for topical use. Caution with prolonged use in severe renal impairment due to gentamicin.

How to Take

Shake well before use. Instill drops into the affected eye or ear. Avoid touching the dropper tip to any surface to prevent contamination.

Mechanism of Action

Fluocinolone Acetonide acts as a potent anti-inflammatory corticosteroid by inhibiting the release of inflammatory mediators. Gentamicin Sulfate is an aminoglycoside antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, leading to bacterial cell death.

Pharmacokinetics

Onset

Within hours for symptomatic relief.

Excretion

Mainly excreted unchanged via kidneys (gentamicin); metabolites excreted via kidneys (fluocinolone).

Half life

Systemic half-life of gentamicin is 2-4 hours; fluocinolone not well characterized systemically after topical use.

Absorption

Minimal systemic absorption following topical ophthalmic or otic administration. Local absorption into ocular/otic tissues.

Metabolism

Primarily metabolized in the liver (gentamicin, some fluocinolone).

Side Effects

Contraindications

Hypersensitivity to fluocinolone, gentamicin, or any component.
Viral infections of the eye/ear (e.g., herpes simplex keratitis).
Fungal infections of the eye/ear.
Mycobacterial infections of the eye/ear.
Untreated purulent infections of the eye/ear.

Drug Interactions

Other ophthalmic/otic preparations

Wait at least 5 minutes between applications.

Storage

Store below 30°C. Do not freeze. Keep out of reach of children. Protect from light.

Overdose

Due to minimal systemic absorption, acute overdose from topical application is unlikely. If accidentally ingested, seek medical advice.

Pregnancy & Lactation

Use with caution during pregnancy and lactation only if potential benefit outweighs potential risk. Consult a doctor.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

5 mL bottle10 mL bottle

Shelf Life

Typically 24-36 months unopened. Discard 28 days after opening.

Availability

Pharmacies and Hospitals

Approval Status

Approved by regulatory authorities

Patent Status

Generic available

Clinical Trials

Specific clinical trials for this combination product generally focus on efficacy and safety in indicated conditions.

Lab Monitoring

Intraocular pressure monitoring (for prolonged ophthalmic use)
Monitoring for signs of secondary infection

Doctor Notes

Monitor patients for signs of increased intraocular pressure, especially with prolonged ophthalmic use (>10 days).
Ensure proper diagnosis to rule out viral/fungal infections before prescribing.

Patient Guidelines

Wash hands before and after application.
Do not wear contact lenses during treatment.
Complete the full course of treatment even if symptoms improve.
Do not share the medicine with others.

Missed Dose Advice

If a dose is missed, apply it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose.