Medicine Information

Fluromet

Name: Fluromet
Brand: Fluromet
Rating: 4.5 (117 reviews)

Ophthalmic Suspension0.1%Ophthalmic CorticosteroidsATC: S01BA07

Generic Name

Fluorometholone Ophthalmic Suspension

Manufacturer

ACME Laboratories Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
fluromet 01 suspension	৳ 100.00	N/A

Description

Overview of the medicine

Fluromet-01 Suspension is an ophthalmic corticosteroid used to treat inflammatory conditions of the eye. It helps to reduce swelling, redness, itching, and irritation in the eye.

Uses & Indications

Treatment of steroid-responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe.

Such conditions include allergic conjunctivitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, selected infective conjunctivitis when the inherent hazard of steroid use is accepted to obtain a diminution in edema and inflammation.

Post-operative inflammation following ocular surgery.

Dosage

Adults

One to two drops instilled into the conjunctival sac of the affected eye(s) two to four times daily. During the initial 24 to 48 hours, the frequency of dosing may be increased to every four hours. Care should be taken not to discontinue therapy prematurely.

Elderly

No specific dosage adjustment is typically required for elderly patients; use adult dosage.

Renal_impairment

Not applicable for topical ophthalmic preparations, as systemic absorption is minimal.

How to Take

Shake the bottle well before use. Tilt your head back, pull down your lower eyelid to form a pouch, and instill the prescribed number of drops. Avoid touching the dropper tip to your eye or any other surface to prevent contamination. Close your eye gently and apply pressure to the inner corner of your eye for a minute or two to prevent the medicine from draining out.

Mechanism of Action

Fluorometholone is a synthetic glucocorticoid that works by inhibiting the release of inflammatory mediators (e.g., prostaglandins, leukotrienes) and by decreasing the migration of leukocytes, thereby reducing inflammation and associated symptoms.

Pharmacokinetics

Onset

Rapid onset of action, typically within a few hours.

Excretion

Excreted locally; minimal systemic excretion via urine and feces.

Half life

Mainly local action; systemic half-life is not clinically significant for topical ophthalmic use.

Absorption

Primarily local absorption into ocular tissues; minimal systemic absorption.

Metabolism

Metabolized primarily within the eye and, if systemically absorbed, in the liver.

Side Effects

Contraindications

Acute untreated purulent bacterial infections of the eye.
Fungal diseases of ocular structures.
Epithelial herpes simplex keratitis (dendritic keratitis).
Vaccinia, varicella, and most other viral diseases of the cornea and conjunctiva.
Mycobacterial infections of the eye.
Hypersensitivity to any component of the medication.

Drug Interactions

Mydriatics/Cycloplegics

May mask signs of infection or inflammation.

Other ophthalmic corticosteroids

Concurrent use of other ophthalmic corticosteroids may increase the risk of elevated intraocular pressure.

Storage

Store upright at room temperature (15-30°C). Protect from light. Do not freeze. Keep out of reach of children.

Overdose

Overdose is unlikely with topical ophthalmic administration. If accidentally ingested, symptomatic and supportive measures should be taken.

Pregnancy & Lactation

Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether topical ophthalmic administration of corticosteroids can result in sufficient systemic absorption to produce detectable quantities in human milk. Exercise caution when administering to a nursing mother.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

5 ml bottle10 ml bottle

Shelf Life

2-3 years (unopened); 28 days after opening.

Availability

Pharmacies, Hospitals

Approval Status

Approved

Patent Status

Expired

Clinical Trials

Fluorometholone has been extensively studied since its introduction, with numerous clinical trials demonstrating its efficacy and safety in treating various steroid-responsive ocular inflammatory conditions. It is known for its relatively low potential to elevate intraocular pressure compared to other corticosteroids.

Lab Monitoring

Regular monitoring of intraocular pressure (IOP), especially with prolonged use (more than 10 days).
Slit lamp examination to monitor for cataract formation or corneal changes.

Doctor Notes

Monitor IOP carefully in patients on prolonged therapy (more than 10 days).
Contraindicated in viral, fungal, or mycobacterial ocular infections unless specifically combined with appropriate anti-infective therapy.
Advise patients not to discontinue abruptly to avoid rebound inflammation.

Patient Guidelines

Shake the bottle well before each use.
Do not wear contact lenses while your eyes are inflamed or during treatment unless advised by your doctor.
Do not share your eye drops with anyone else.
Report any worsening of symptoms or new eye problems to your doctor immediately.
Do not use for longer than prescribed by your doctor to avoid serious side effects.

Missed Dose Advice

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.

Driving Precautions

This medicine may cause temporary blurred vision or other visual disturbances immediately after instillation. If affected, do not drive or operate machinery until your vision clears.

Lifestyle Advice

Avoid rubbing your eyes.
Maintain good hand hygiene to prevent further infection or irritation.
If you wear contact lenses, avoid wearing them during treatment for acute inflammation.