Medicine Information

Gatsina

Name: Gatsina
Brand: Gatsina
Rating: 4.5 (117 reviews)

Eye Drop0.3% w/vOphthalmic AntibioticsATC: S01AE06

Generic Name

Gatifloxacin

Manufacturer

Square Pharmaceuticals Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
gatsina 03 eye drop	৳ 100.00	N/A

Description

Overview of the medicine

Gatifloxacin is a broad-spectrum fluoroquinolone antibiotic indicated for the treatment of bacterial conjunctivitis.

Uses & Indications

Bacterial conjunctivitis

Other susceptible ocular bacterial infections (off-label)

Dosage

Adults

Instill 1 drop into the affected eye(s) every 2 hours while awake, up to 8 times a day on day 1, then 1 drop 2 to 4 times a day on days 2-7.

Elderly

No specific dosage adjustment required for elderly patients.

Renal_impairment

No specific dosage adjustment required as systemic absorption is minimal.

How to Take

For ophthalmic use only. Wash hands before use. Do not touch the dropper tip to any surface.

Mechanism of Action

Gatifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication, transcription, repair, and recombination, leading to bacterial cell death.

Pharmacokinetics

Onset

Rapid onset of action, typically within hours.

Excretion

Primarily renal for systemically absorbed drug, but very little is absorbed from ophthalmic use.

Half life

Not well characterized for ophthalmic use due to minimal systemic absorption; estimated around 5-8 hours for systemic.

Absorption

Minimal systemic absorption following ocular administration.

Metabolism

Minimal systemic metabolism.

Side Effects

Contraindications

Hypersensitivity to gatifloxacin or other fluoroquinolones
Viral or fungal eye infections

Drug Interactions

No significant ophthalmic drug interactions reported

Due to minimal systemic absorption, significant ophthalmic drug interactions are not expected.

Storage

Store at room temperature (below 30°C), away from light and moisture. Do not freeze. Keep out of reach of children.

Overdose

Overdose is unlikely with ophthalmic use. If accidentally ingested, seek medical advice.

Pregnancy & Lactation

Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution should be exercised when administered to a nursing woman.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

5 ml dropper bottle

Shelf Life

Typically 24 months (unopened), 28 days after opening.

Availability

Pharmacies, hospitals, clinics

Approval Status

Approved by relevant regulatory authorities

Patent Status

Off-patent

WHO Essential Medicine

Yes

Clinical Trials

Clinical trials have demonstrated efficacy and safety of Gatifloxacin ophthalmic solution in the treatment of bacterial conjunctivitis caused by susceptible strains of microorganisms.

Lab Monitoring

No specific lab monitoring required for ophthalmic use.

Doctor Notes

Emphasize patient compliance to the full course of therapy to prevent antibiotic resistance.
Advise patients on proper instillation technique to avoid contamination and maximize efficacy.
Monitor for signs of allergic reaction or worsening infection.

Patient Guidelines

Do not wear contact lenses during treatment.
Avoid contaminating the dropper tip.
Complete the full course of treatment even if symptoms improve.
Do not share the eye drop with others.

Missed Dose Advice

If a dose is missed, apply it as soon as possible. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.