Medicine Information

Hexizen

Name: Hexizen
Brand: Hexizen
Rating: 4.5 (117 reviews)

Hand Rub Solution0.5% w/v Chlorhexidine Gluconate, 70% v/v Ethyl AlcoholAntiseptic & DisinfectantATC: D08AC52

Generic Name

Chlorhexidine Gluconate 0.5% w/v & Ethyl Alcohol 70% v/v Hand Rub

Manufacturer

Example Pharma Ltd.

Country

Bangladesh

Loading images...

Price Details

Current market pricing information

Variant	Unit Price	Strip Price
hexizen 05 70 hand rub	৳ 40.00	N/A

Description

Overview of the medicine

Hexizen-05-70-hand-rub is an antiseptic solution used for rapid hand disinfection. It contains Chlorhexidine Gluconate and Ethyl Alcohol, offering a broad spectrum of antimicrobial activity against bacteria, viruses, and fungi.

Uses & Indications

Surgical hand antisepsis

Routine hygienic hand antisepsis

Pre-operative skin preparation (adjunct)

Dosage

Adults

For hygienic hand rub: Apply 3 ml to dry hands, rub for 30 seconds. For surgical hand rub: Apply 5 ml to hands and forearms, rub for 2-3 minutes, repeat if necessary.

Elderly

Same as adult dosage.

Renal_impairment

Not applicable as systemic absorption is minimal.

How to Take

For external use only. Apply undiluted to clean, dry hands. Rub thoroughly until dry. Do not rinse with water.

Mechanism of Action

Chlorhexidine Gluconate acts by disrupting bacterial cell membranes and precipitating cell contents. Ethyl Alcohol denatures proteins and solubilizes lipids, causing cell lysis and rapid microbial death. The combination provides synergistic action and residual effect.

Pharmacokinetics

Onset

Immediate (within seconds for alcohol, residual for chlorhexidine).

Excretion

Primarily remains on the skin surface; minimal excretion if absorbed.

Half life

Not applicable for topical hand rub; residual activity of chlorhexidine lasts hours.

Absorption

Minimal systemic absorption through intact skin.

Metabolism

Not systemically metabolized to a significant extent.

Side Effects

Contraindications

Hypersensitivity to chlorhexidine, alcohol, or any component
Open wounds or damaged skin (due to potential for systemic absorption and irritation)
Avoid contact with eyes, brain, meninges, or middle ear

Drug Interactions

Soap and other anionic agents

May neutralize the effect of chlorhexidine.

Storage

Store below 30°C in a cool, dry place. Protect from direct sunlight and heat. Keep container tightly closed.

Overdose

Topical overdose is unlikely to cause systemic toxicity. Ingested large quantities may lead to alcohol intoxication and chlorhexidine toxicity (e.g., irritation of mucous membranes, stomach upset). Seek medical attention if ingested.

Pregnancy & Lactation

Considered safe for use during pregnancy and lactation as systemic absorption is minimal. Consult a healthcare professional if concerned.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

50 ml bottle100 ml bottle250 ml bottle500 ml bottle1 Liter bottle

Shelf Life

Typically 2-3 years from manufacturing date.

Availability

Pharmacies, hospitals, clinics, general stores

Approval Status

Approved

Patent Status

Expired/Generic

WHO Essential Medicine

Yes

Clinical Trials

Extensively studied and demonstrated efficacy in numerous clinical trials for hand antisepsis.

Lab Monitoring

Not typically required for routine hand rub use.

Doctor Notes

Emphasize correct hand hygiene technique.
Advise patients about potential for skin dryness and the use of moisturizers.
Caution against use on broken skin or mucous membranes.

Patient Guidelines

For external use only. Do not swallow.
Avoid contact with eyes. If contact occurs, rinse thoroughly with water.
Keep out of reach of children.
Flammable: Keep away from heat and open flame.

Missed Dose Advice

As this is an on-demand antiseptic, apply when needed. There is no 'missed dose' in the conventional sense.

Driving Precautions

No known effects on driving ability.

Lifestyle Advice

Maintain good hand hygiene practices, especially before eating and after using the restroom.
Use moisturizers if skin dryness occurs.

Alternative Medicines in Bangladesh

Similar medicines available in the market

Sterilium (Square Pharma)Acne Aid Liquid Cleanser (ACI Pharmaceuticals) - different use but similar componentPoviwash (Beximco Pharma) - different antiseptic