Medicine Information

Hiposul

Name: Hiposul
Brand: Hiposul
Rating: 4.5 (117 reviews)

Syrup5 mg/5 mlAntihistamine, Second GenerationATC: R06AE10

Generic Name

HypoSulfonate 5 mg/5 ml syrup

Manufacturer

PharmaCorp Bangladesh Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
hiposul 5 mg syrup	৳ 62.00	N/A

Description

Overview of the medicine

Hiposul 5 mg syrup is an antihistamine used to relieve symptoms of allergic conditions such as seasonal allergies, perennial allergic rhinitis, and chronic idiopathic urticaria.

Uses & Indications

Seasonal allergic rhinitis

Perennial allergic rhinitis

Chronic idiopathic urticaria

Dosage

Adults

10 ml (10 mg) once daily.

Elderly

No specific dose adjustment required, but caution advised for renal impairment.

Renal_impairment

For moderate to severe renal impairment, dose adjustment may be necessary. Consult a physician.

How to Take

Take orally, with or without food. Use the provided measuring spoon or cup for accurate dosing.

Mechanism of Action

Hiposul acts as a selective H1-receptor antagonist, blocking the action of histamine, a chemical mediator responsible for allergic symptoms like itching, sneezing, and runny nose.

Pharmacokinetics

Onset

1-2 hours

Excretion

Primarily excreted unchanged in urine and feces

Half life

Approximately 8-12 hours

Absorption

Rapidly absorbed from the gastrointestinal tract; peak plasma concentrations reached within 1 hour.

Metabolism

Minimal hepatic metabolism

Side Effects

Contraindications

Hypersensitivity to Hiposul or any of its components
Severe renal impairment (creatinine clearance less than 10 ml/min)

Drug Interactions

Ritonavir

May increase plasma concentrations of Hiposul.

Alcohol and CNS depressants

May enhance drowsiness and impair performance.

Storage

Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.

Overdose

Symptoms of overdose may include drowsiness, tachycardia, and urinary retention. Treatment is symptomatic and supportive; no specific antidote.

Pregnancy & Lactation

Pregnancy Category B. Use only if clearly needed. Excreted in breast milk, caution advised for lactating mothers. Consult a doctor before use.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

60 ml syrup100 ml syrup

Shelf Life

24 months from manufacturing date.

Availability

Pharmacies, Hospitals

Approval Status

Approved by regulatory authority (e.g., DGDA)

Patent Status

Patent expired, generic available

Clinical Trials

Extensive clinical trials have demonstrated efficacy and safety in various allergic conditions. Post-marketing surveillance data also supports its use.

Lab Monitoring

No routine lab monitoring typically required.

Doctor Notes

Advise patients on potential for drowsiness, especially initially.
Review renal function in elderly or patients with pre-existing renal impairment.
Counsel on avoiding concurrent alcohol use.

Patient Guidelines

Do not exceed the recommended dose.
Avoid driving or operating machinery if you experience drowsiness.
Inform your doctor about all other medications you are taking.

Missed Dose Advice

If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.