Medicine Information

Irovit-Z

Name: Irovit-Z
Brand: Irovit-Z
Rating: 4.5 (117 reviews)

SyrupElemental Iron 50 mg + Elemental Zinc 20 mg + B-Complex Vitamins per 5 mlAnti-anemic Preparations / Vitamin & Mineral SupplementsATC: B03AE10

Generic Name

Polymaltose Iron Complex + Zinc + B-Complex Vitamins

Manufacturer

ACI Limited

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
irovit z syrup	৳ 50.00	N/A

Description

Overview of the medicine

Irovit-Z Syrup is a nutritional supplement formulated to address iron, zinc, and B-vitamin deficiencies. It helps in the formation of red blood cells, supports immune function, and contributes to overall growth and development.

Uses & Indications

Iron deficiency anemia

Zinc deficiency

Vitamin B deficiency

General nutritional supplementation during pregnancy, lactation, or growth spurts

Convalescence

Dosage

Adults

10 ml (2 teaspoonfuls) once daily or as directed by the physician.

Elderly

Same as adult dosage, or as directed by the physician.

Renal_impairment

Use with caution. Dosage adjustment may be required in severe renal impairment. Consult physician.

How to Take

Administer orally. Can be taken with or without food. Taking it with food may reduce gastrointestinal discomfort. Shake well before use.

Mechanism of Action

Iron is crucial for hemoglobin synthesis and oxygen transport. Zinc is involved in numerous enzymatic reactions, immune function, and cell growth. B-complex vitamins (e.g., B1, B2, B3, B6, B12) play vital roles in energy metabolism, neurological function, and red blood cell formation.

Pharmacokinetics

Onset

Clinical improvement may be seen within weeks, depending on the severity of deficiency.

Excretion

Iron is minimally excreted. Zinc is primarily excreted via feces. B-vitamins are excreted mainly via urine.

Half life

Variable for individual components. Iron's biological half-life is long due to recycling; Zinc is about 120 days in the body; B-vitamins vary from hours to days.

Absorption

Polymaltose Iron Complex is absorbed primarily in the duodenum, often via a non-heme pathway, leading to less gastrointestinal irritation. Zinc absorption occurs mainly in the small intestine. B-vitamins are generally well absorbed from the gastrointestinal tract.

Metabolism

Iron is primarily stored in ferritin and hemosiderin. Zinc is largely bound to proteins. B-vitamins are metabolized in the liver and active forms are produced.

Side Effects

Contraindications

Hypersensitivity to any component of the formulation
Hemochromatosis or other iron overload disorders
Active peptic ulcer, regional enteritis, or ulcerative colitis

Drug Interactions

Antacids

Can decrease iron absorption. Avoid concomitant use.

Levothyroxine

Iron may decrease levothyroxine absorption. Separate administration by at least 4 hours.

Penicillamine

Zinc can reduce its absorption. Separate doses.

Tetracyclines & Quinolones

Iron and Zinc can reduce the absorption of these antibiotics. Take Iron/Zinc at least 2 hours before or 4-6 hours after.

Storage

Store in a cool and dry place, below 30°C. Protect from light. Do not freeze.

Overdose

Symptoms of overdose may include severe nausea, vomiting, abdominal pain, diarrhea, lethargy, pallor, and potentially shock. In severe cases, iron overdose can lead to metabolic acidosis, cardiovascular collapse, and liver damage. Seek immediate medical attention. Management involves supportive care, gastric lavage, and chelating agents (e.g., deferoxamine) if iron toxicity is severe.

Pregnancy & Lactation

Generally considered safe and often recommended during pregnancy and lactation to meet increased nutritional demands. Consult a physician before use.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

100 ml syrup bottle200 ml syrup bottle

Shelf Life

24-36 months from manufacturing date, refer to packaging.

Availability

Pharmacies, drugstores, supermarkets

Approval Status

Approved by DGDA (Bangladesh)

Patent Status

Off-patent

WHO Essential Medicine

Yes

Clinical Trials

Specific clinical trials for Irovit-Z Syrup are usually focused on bioavailability and efficacy in target populations for iron/zinc/vitamin deficiencies. Data often supports the use of polymaltose iron complex for better GI tolerance.

Lab Monitoring

Complete Blood Count (CBC) including Hemoglobin and Hematocrit
Serum Ferritin levels
Serum Iron and Total Iron Binding Capacity (TIBC)
Serum Zinc levels

Doctor Notes

Advise patients about potential dark stools and mild GI upset.
Emphasize not to exceed recommended dosage due to iron toxicity risk.
Consider dietary counseling to enhance nutrient intake.

Patient Guidelines

Take as directed by your physician or pharmacist.
Do not exceed the recommended dose.
Keep out of reach of children.
Report any severe side effects to your doctor.

Missed Dose Advice

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not double the dose to catch up.

Driving Precautions

No known specific precautions for driving or operating machinery. Generally, it does not cause drowsiness or impair judgment.

Lifestyle Advice

Maintain a balanced diet rich in iron, zinc, and vitamins.
Ensure adequate hydration.
For better iron absorption, consume foods rich in Vitamin C (e.g., citrus fruits).